[HTML][HTML] Hydrogen sulfide metabolite, sodium thiosulfate: clinical applications and underlying molecular mechanisms

…, GJ Dugbartey, S Juriasingani, A Sener - International journal of …, 2021 - mdpi.com
Thiosulfate in the form of sodium thiosulfate (STS) is a major oxidation product of hydrogen
sulfide (H 2 S), an endogenous signaling molecule and the third member of the …

Renal perfusion pump vs cold storage for donation after cardiac death kidneys: a systematic review

…, T McGregor, VC McAlister, PPW Luke, A Sener - The Journal of …, 2013 - Elsevier
PURPOSE: Static cold storage is generally used to preserve kidney allografts from deceased
donors. Hypothermic machine perfusion may improve the outcome after transplantation but …

H2S donor molecules against cold ischemia-reperfusion injury in preclinical models of solid organ transplantation

…, S Juriasingani, MY Zhang, A Sener - Pharmacological …, 2021 - Elsevier
Cold ischemia-reperfusion injury (IRI) is an inevitable and unresolved problem that poses a
great challenge in solid organ transplantation (SOT). It represents a major factor that …

Intravenous immunoglobulin as a treatment for BK virus associated nephropathy: one-year follow-up of renal allograft recipients

A Sener, AA House, AM Jevnikar, N Boudville… - …, 2006 - journals.lww.com
BK virus associated nephropathy (BKVAN) has emerged as an important cause of renal
allograft dysfunction and graft loss. Although several treatment strategies have been proposed, …

Hydrogen sulfide treatment mitigates renal allograft ischemia-reperfusion injury during cold storage and improves early transplant kidney function and survival …

…, W Liu, A Haig, L Gunaratnam, A Sener - The Journal of …, 2015 - auajournals.org
Purpose : Ischemia-reperfusion injury is unavoidable during organ transplantation. Prolonged
ischemia-reperfusion injury is detrimental to short-term and long-term graft function and …

Cardiovascular risk in men with prostate cancer: insights from the RADICAL PC study

…, AK Hameed, H Abdel-Qadir, A Sener… - The Journal of …, 2020 - auajournals.org
Purpose: We describe the cardiovascular risk profile in a representative cohort of patients
with prostate cancer treated with or without androgen deprivation therapy. Materials and …

[HTML][HTML] Kidney injury molecule-1 protects against Gα12 activation and tissue damage in renal ischemia-reperfusion injury

…, J Wei, A Haig, BM Denker, RS Suri, A Sener… - The American journal of …, 2015 - Elsevier
Ischemic acute kidney injury is a serious untreatable condition. Activation of the G protein α12
(Gα12) subunit by reactive oxygen species is a major cause of tissue damage during renal …

Renal protection against ischemia reperfusion injury: hemoglobin-based oxygen carrier-201 versus blood as an oxygen carrier in ex vivo subnormothermic machine …

…, S Aquil, R Al-Ogaili, S Juriasingani, A Sener… - …, 2020 - journals.lww.com
Background. The optimal method of oxygen delivery to donor kidneys during ex vivo machine
perfusion has not been established. We have recently reported the beneficial effects of …

Supplemental hydrogen sulphide protects transplant kidney function and prolongs recipient survival after prolonged cold ischaemia–reperfusion injury by mitigating …

…, A Mok, Z Lan, W Liu, B Garcia, A Sener - BJU international, 2012 - Wiley Online Library
What's known on the subject? and What does the study add? Hydrogen sulphide (H 2 S)
has recently been classified as a member of the family of small gaseous molecules called …

[HTML][HTML] Sodium thiosulfate-supplemented UW solution protects renal grafts against prolonged cold ischemia-reperfusion injury in a murine model of syngeneic kidney …

…, W Liu, A Haig, P McLeod, J Arp, A Sener - Biomedicine & …, 2022 - Elsevier
Introduction Cold ischemia-reperfusion injury (IRI) is an inevitable event that increases post-transplant
complications. We have previously demonstrated that supplementation of …