User profiles for Alex Haines
Alexander HainesCADTH Verified email at cadth.ca Cited by 473 |
Identification, assessment, and management of overweight and obesity: summary of updated NICE guidance
… Heather Stegenga systematic reviewer1, Alexander Haines health economist2, Katie
Jones senior … Haines@rcplondon.ac.uk … The members of the Guideline Development …
Jones senior … Haines@rcplondon.ac.uk … The members of the Guideline Development …
The UDP-glycosyltransferase (UGT) superfamily: new members, new functions, and novel paradigms
…, SN Mubarokah, AZ Haines… - Physiological …, 2019 - journals.physiology.org
UDP-glycosyltransferases (UGTs) catalyze the covalent addition of sugars to a broad range
of lipophilic molecules. This biotransformation plays a critical role in elimination of a broad …
of lipophilic molecules. This biotransformation plays a critical role in elimination of a broad …
[HTML][HTML] An economic evaluation of vector control in the age of a dengue vaccine
Introduction Dengue is a rapidly emerging vector-borne Neglected Tropical Disease, with a
30-fold increase in the number of cases reported since 1960. The economic cost of the …
30-fold increase in the number of cases reported since 1960. The economic cost of the …
The UGTome: The expanding diversity of UDP glycosyltransferases and its impact on small molecule metabolism
The UDP glycosyltransferase (UGT) superfamily of enzymes is responsible for the
metabolism and clearance of thousands of lipophilic chemicals including drugs, toxins and …
metabolism and clearance of thousands of lipophilic chemicals including drugs, toxins and …
[HTML][HTML] Antiviral treatment for treatment-naïve chronic hepatitis B: systematic review and network meta-analysis of randomized controlled trials
…, P Pechivanoglou, J Wong, JM Bielecki, A Haines… - Systematic …, 2019 - Springer
Background Chronic hepatitis B (CHB) infection poses a significant burden to public health
worldwide. Most cases are clinically silent until late in the disease course. The main goal of …
worldwide. Most cases are clinically silent until late in the disease course. The main goal of …
Cost effectiveness of advanced pharmacy services provided in the community and primary care settings: a systematic review
Background Pharmacists working in community and primary care are increasingly developing
advanced skills to provide enhanced services, particularly in dealing with minor acute …
advanced skills to provide enhanced services, particularly in dealing with minor acute …
Health care costs associated with chronic hepatitis C virus infection in Ontario, Canada: a retrospective cohort study
WWL Wong, A Haines, KE Bremner, Z Yao… - … Open Access Journal, 2021 - cmajopen.ca
Background: High-quality estimates of health care costs are required to understand the
burden of illness and to inform economic models. We estimated the costs associated with …
burden of illness and to inform economic models. We estimated the costs associated with …
Estimating chronic hepatitis C prevalence in British Columbia and Ontario, Canada, using population‐based cohort studies
Patients identified as having chronic hepatitis C (CHC) infection can be effectively and rapidly
treated using direct‐acting antiviral agents. However, there remains a substantial burden …
treated using direct‐acting antiviral agents. However, there remains a substantial burden …
[HTML][HTML] A province-by-province cost-effectiveness analysis and budget impact analysis of one-time birth cohort screening of hepatitis C virus (HCV) infection in …
Managing chronic hepatitis C is challenging, as the majority of those infected are
asymptomatic. Therefore, to ensure treatments are administered before the onset of severe …
asymptomatic. Therefore, to ensure treatments are administered before the onset of severe …
Can we afford not to screen and treat hepatitis C virus infection in Canada?
WWL Wong, A Haines… - Canadian Liver …, 2018 - canlivj.utpjournals.press
Background Screening for hepatitis C virus (HCV) followed by direct-acting antiviral (DAA)
treatment in individuals born between 1945 and 1964 has been shown to be both effective …
treatment in individuals born between 1945 and 1964 has been shown to be both effective …