Insulin resistance (IR) is common in chronic hemodialysis (CHD) patients and is associated
with excess mortality. The gold standard for assessment of insulin sensitivity is …

Objective To better define the prevalence of protein-energy wasting (PEW) in kidney
disease is poorly defined. Methods We performed a meta-analysis of PEW prevalence from …

Chronic inflammation is highly prevalent in maintenance hemodialysis (MHD) patients and
associates with increased mortality. IL-1β, a pro-inflammatory cytokine, is elevated in MHD …

Diabetes is a major cause of chronic kidney disease, and oral antidiabetic drugs are the
mainstay of therapy for most patients with Type 2 diabetes. Here we evaluated their role on …

Trials raising concerns about erythropoiesis-stimulating agents, revisions to their labeling,
and changes to practice guidelines and dialysis payment systems have provided strong …

Urea removal has become a key measure of the intensity of dialysis treatment for kidney failure.
Small solute removal, exemplified by Kt/V urea, has been broadly applied as a means to …

Background: The effects of sulfonylureas and metformin on outcomes of cardiovascular disease
(CVD) in type 2 diabetes are not well-characterized. Objective: To compare the effects of …

In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood
pressure to identify genes, tissues, phenomes and medication contexts of blood pressure …

Results Agreement between estimating methods and the reference standard was highest
when using creatinine values measured 7–365 days before admission. During this interval, the …

Background: Cross-sectional studies have shown an association between the duration (y)
of dialysis and nutritional status, providing evidence of wasting. Objective: The aim was to …