[HTML][HTML] Screening for cervical cancer: should we test for infection with high-risk HPV?

CJLM Meijer, PJF Snijders, A Brule - Cmaj, 2000 - Can Med Assoc
Commentary Commentaire about 12.7 years. 8 Because persistent infection with highrisk
HPV is necessary for the development of CIN, the mean time between initial infection and …

Comparison of quantitative competitive PCR with LightCycler-based PCR for measuring Epstein-Barr virus DNA load in clinical specimens

…, SAWM Verkuijlen, AJC Brule… - Journal of clinical …, 2002 - Am Soc Microbiol
The aim of this study was to develop a LightCycler-based real-time PCR assay for monitoring
the Epstein-Barr virus (EBV) DNA load in unfractionated whole blood. This assay was …

The use of general primers GP5 and GP6 elongated at their 3′ ends with adjacent highly conserved sequences improves human papillomavirus detection by PCR

…, AJC van den Brule… - Journal of general …, 1995 - microbiologyresearch.org
Sequence analysis of human papillomavirus (HPV) general primer GP5/6 mediated PCR
products revealed the presence of short highly conserved sequences adjacent to the 3′ ends …

[HTML][HTML] Sexually transmitted infection as a cause of anal cancer

M Frisch, B Glimelius, AJC van den Brule… - … England Journal of …, 1997 - Mass Medical Soc
Background The incidence of anal cancer has increased in recent decades, particularly
among women. To identify underlying risk factors, we conducted a population-based case–…

GP5+/6+ PCR followed by reverse line blot analysis enables rapid and high-throughput identification of human papillomavirus genotypes

AJC van den Brule, R Pol… - Journal of clinical …, 2002 - Am Soc Microbiol
In this study, we developed a simple and fast typing procedure for 37 mucosotropic human
papillomavirus (HPV) types using a nonradioactive reverse line blotting (RLB) procedure for …

Type specific persistence of high risk human papillomavirus (HPV) as indicator of high grade cervical squamous intraepithelial lesions in young women: population …

SK Kjaer, AJC Van den Brule, G Paull, EI Svare… - Bmj, 2002 - bmj.com
Objectives: To investigate the role of human papillomavirus (HPV) in the development of
cervical neoplasia in women with no previous cervical cytological abnormalities; whether the …

Herpes simplex virus-2 as a human papillomavirus cofactor in the etiology of invasive cervical cancer

…, CJLM Meijer, AJC Van den Brule… - Journal of the …, 2002 - academic.oup.com
Background: Human papillomavirus (HPV) infection is the main cause of invasive cervical
cancer, but cofactors may act in conjunction with HPV. We performed a pooled analysis of …

The use of general primers in the polymerase chain reaction permits the detection of a broad spectrum of human papillomavirus genotypes

PJF Snijders, AJC van den Brule… - Journal of General …, 1990 - microbiologyresearch.org
A novel polymerase chain reaction (PCR) method was developed that permits the detection
of 11 different human papillomavirus (HPV) genotypes using two general primer sets. By …

Determinants of clearance of human papillomavirus infections in Colombian women with normal cytology: a population-based, 5-year follow-up study

M Molano, A Van den Brule, M Plummer… - American journal of …, 2003 - academic.oup.com
Little is known about the factors that influence clearance of human papillomavirus (HPV),
the primary cause of cervical carcinoma. A total of 227 women cytologically normal and HPV …

High-risk human papillomavirus is sexually transmitted: evidence from a follow-up study of virgins starting sexual activity (intercourse)

…, B Chackerian, AJC Van Den Brule… - … Biomarkers & Prevention, 2001 - AACR
Genital human papillomavirus (HPV) infection is generally considered to be sexually
transmitted. However, nonsexual spread of the virus has also been suggested. The goal of this …