With improved life expectancy of cystic fibrosis (CF) patients, CF-related diabetes (CFRD)
has become a major complication. The oral glucose tolerance test (OGTT) is the standard test …

Nearly 50% of adult patients with cystic fibrosis (CF) have diabetes. The occurrence of CF-related
diabetes (CFRD) is preceded and is associated with deterioration of lung function and …

Background: Most patients with type 1 diabetes do not achieve their glycemic targets. We
aimed to assess the efficacy of glucose-responsive insulin and glucagon closed-loop delivery …

Cystic Fibrosis-Related Diabetes (CFRD) is a unique type of diabetes mellitus that shares
some features with both type 1 and type 2 diabetes. Yet, its distinguishing feature of acute …

Background Aging cystic fibrosis (CF) patients are at high risk of developing CF-related
diabetes (CFRD). Decrease in insulin secretion over time is the main hypothesis to explain this …

Background Reduced insulin secretion is a key factor to explain high prevalence of glucose
intolerance in patients with cystic fibrosis (CF). However, the role of insulin sensitivity …

Background CFRD is preceded and associated with a significantly increased morbidity and
mortality. We aimed to characterize a large newly established glucose tolerance subgroup …

Context: Cystic fibrosis-related diabetes is primarily due to a defect in insulin secretion.
Women with cystic fibrosis (CF) are at higher risk of developing CF-related diabetes. Objective: …

Aims Cystic fibrosis (CF) is associated with the emergence of CF-related diabetes (CFRD).
CFRD is associated with increased risk of accelerated weight and/or lung function loss (…

Up-regulation of utrophin in muscles represents a promising therapeutic strategy for the
treatment of Duchenne Muscular Dystrophy. We previously demonstrated that eEF1A2 …