User profiles for Abdelbaset A. Elzagallaai

Abdelbaset A. Elzagallaai

Adjunct Professor, Western University
Verified email at uwo.ca
Cited by 1133

Hair cortisol analysis: An update on methodological considerations and clinical applications

MJE Greff, JM Levine, AM Abuzgaia, AA Elzagallaai… - Clinical …, 2019 - Elsevier
Background Hair cortisol analysis is increasingly being appreciated and applied in both
research and medicine, aiding endocrinologists with diagnosis. Content We provide an …

Adverse drug reactions in children: the double‐edged sword of therapeutics

AA Elzagallaai, MJE Greff… - Clinical Pharmacology & …, 2017 - Wiley Online Library
Adverse drug reactions (ADRs) represent a major health problem worldwide, with high
morbidity and mortality rates. ADRs are classified into Type A (augmented) and Type B (bizarre) …

Patch testing for the diagnosis of anticonvulsant hypersensitivity syndrome: a systematic review

AA Elzagallaai, SR Knowles, MJ Rieder, JR Bend… - Drug safety, 2009 - Springer
Anticonvulsant hypersensitivity syndrome (AHS), also known by the other names drug rash (reaction)
with eosinophilia and systemic symptoms (DRESS) and drug-induced …

[HTML][HTML] War exposure, post-traumatic stress symptoms and hair cortisol concentrations in Syrian refugee children

…, J Fayyad, D Saab, MJ Rieder, AA Elzagallaai… - Molecular …, 2023 - nature.com
Altered secretion of cortisol, the primary effector of the hypothalamus–pituitary–adrenal axis,
has been proposed as a means by which traumatic experiences compromise later mental …

Role of oxidative stress in hypersensitivity reactions to sulfonamides

AA Elzagallaai, EA Sultan, JR Bend… - The Journal of …, 2020 - Wiley Online Library
Antimicrobial sulfonamides are important medications. However, their use is associated with
major immune‐mediated drug hypersensitivity reactions with a rate that ranges from 3% to 4…

[HTML][HTML] The role of environmental sensitivity in the mental health of Syrian refugee children: a multi-level analysis

…, F McEwen, E Karam, MJ Rieder, AA Elzagallaai… - Molecular …, 2024 - nature.com
Individuals with high environmental sensitivity have nervous systems that are disproportionately
receptive to both the protective and imperilling aspects of the environment, suggesting …

In Vitro Testing for the Diagnosis of Anticonvulsant Hypersensitivity Syndrome: A Systematic Review

AA Elzagallaai, SR Knowles, MJ Rieder… - Molecular diagnosis & …, 2009 - Springer
Anticonvulsant hypersensitivity syndrome (AHS) is a rare and potentially fatal reaction that
develops in susceptible patients following exposure to certain drugs, including aromatic …

Risk and resilience in Syrian refugee children: A multisystem analysis

…, EG Karam, MJ Rieder, AA Elzagallaai… - Development and …, 2023 - cambridge.org
Refugee children are often exposed to substantial trauma, placing them at increased risk for
mental illness. However, this risk can be mitigated by a capacity for resilience, conferred …

Pathophysiology of drug hypersensitivity

AA Elzagallaai, MJ Rieder - British Journal of Clinical …, 2022 - Wiley Online Library
Drug hypersensitivity reactions (DHRs) are type B adverse drug reactions (ADRs) traditionally
defined as unpredictable, dose independent and not related to the drug pharmacology. …

In vitro testing for diagnosis of idiosyncratic adverse drug reactions: Implications for pathophysiology

AA Elzagallaai, MJ Rieder - British journal of clinical …, 2015 - Wiley Online Library
Idiosyncratic drug reactions (IDRs) represent a major health problem, as they are
unpredictable, often severe and can be life threatening. The low incidence of IDRs makes their …