… Am J Physiol Regul Integr Comp Physiol 2009; 296:R1598–R1605. Heat stress does not
impair the ability to control cerebral perfusion after a rapid reduction in perfusion pressure …

JR was a 72-year-old man who presented for elective replacement of his right hip. He was
still working as an accountant and had been physically active, including playing tennis, until …

Mature cystic teratomas (MCT), commonly called dermoid cysts, are the most common
benign germ cell tumors of the ovary in women of reproductive age. Future fertility is of major …

Background and Purpose Cerebral autoregulation can be evaluated by measuring relative
blood flow changes in response to a steady-state change in the blood pressure (static method…

Hepatitis C virus (HCV) is a global health problem requiring novel approaches for effective
treatment of this disease. The HCV NS5B polymerase has been demonstrated to be a viable …

✓ To examine the relationship between serum glucose and the outcome of patients suffering
from head injury, the authors retrospectively reviewed the clinical course of 169 patients …

✓ The purpose of this study was to determine whether patients with minor head injury experience
impairments in cerebral autoregulation. Twenty-nine patients with minor head injuries …

A phosphoramidate prodrug of 2′-deoxy-2′-α-fluoro-β-C-methyluridine-5′-monophosphate,
PSI-7851, demonstrates potent anti-hepatitis C virus (HCV) activity both in vitro and in …

PSI-7977, a prodrug of 2′-F-2′-C-methyluridine monophosphate, is the purified
diastereoisomer of PSI-7851 and is currently being investigated in phase 3 clinical trials for the …

The hepatitis C virus (HCV) NS5B RNA polymerase facilitates the RNA synthesis step during
the HCV replication cycle. Nucleoside analogs targeting the NS5B provide an attractive …