Multiple sclerosis (MS) is probably aetiologically heterogeneous. Systematic genetic
epidemiological and molecular genetic studies have provided important insights. Both genetic and …

… AD Sadovnick and GC Ebers … Sweeney VP, Sadovnick AD, Brandejs V. Prevalence of
multiple sclerosis in … Sadovnick AD, Ebers GC. Age of onset in siblings concordant for multiple …

… Reduced incidence of AD with NSAID but not H 2 receptor antagonists. The Cache County
… Naproxen and celecoxib do not prevent AD in early results from a randomized controlled …

Frontotemporal dementia (FTD) is the second most common cause of dementia in people
under the age of 65 years 1 . A large proportion of FTD patients (35–50%) have a family history …

Background Incidence of multiple sclerosis is thought to be increasing, but this notion has
been difficult to substantiate. In a longitudinal population-based dataset of patients with …

GENETIC-environmental interactions probably underlie spontaneous human autoimmune
disorders, a category of complex traits thought to include multiple sclerosis (MS) 1 . The …

Size and ascertainment constraints often limit twin studies to concordance comparisons between
identical and fraternal twins. Here we report the final results of a longitudinal, population…

Article abstract-The objectives of the present study were (1) to ascertain the lifetime risk of a
depression in n representative group of multiple sclerosis (MS) patients,(2) to assess the …

Results from studies of twin concordance in multiple sclerosis have not conclusively differentiated
between environmental and genetic factors that determine susceptibility to the disease…

This study is a 7.5 year follow‐up of a population‐based series of twins with multiple sclerosis
(MS) whose mean age now exceeds 50 years. The twin pairs were identified through the …