Since the identification of 2‐phenylethylamine (β‐phenylethylamine; PE) as a biogenic amine,
there has been much discussion about what role, if any, it may have in the CNS. Indeed, …

Classically, aromaticl-amino acid decarboxylase (AADC) has been regarded as an unregulated,
rather uninteresting enzyme. In this review, we describe advances made during the past …

Schizophrenia is a devastating disorder that has been referred to as youth's greatest
disabler. Although a number of hypotheses have been proposed in an attempt to explain the …

A series of aliphaticpropargylamine derivatives has been synthesized. Some of them possess
highly potent, irreversible, selective, inhibitory activity toward monoamineoxidase B (MAO-…

Two series of drugs, the aliphatic-N-methyl propargylamines and the aliphatic propargylamines,
have been synthesised and shown to be specific, irreversible, and potent monoamine …

β‐Phenylethylamine (PE) hydrochloride injected intraperitoneally into rats was distributed
evenly throughout the various regions of rat brain. Similarly, when a mixture of PE and α, α, β, β…

Postmortem human brains have been obtained from four nonpsychiatric patients, aged 59-70
years. Regional analysis of the trace amines phenylethylamine, p-tyramine, m-tyramine, …

Glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) has long been recognized as
playing an integral role in glycolysis. During the past 20 years, however, a number of novel, …

Behavioral and pharmacological effects of oral administration ofl-deprenyl in the dog are
described. Spontaneous behavior is unaffected at doses below 3 mg/kg while at higher doses …

A procedure for the quantitative evaluation of some amines present in mammalian tissues
has been developed. It includes isolation of the amines by ion exchange chromatography …