Dextromethorphan (DM) is a commonly used antitussive and is currently the only FDA-
approved pharmaceutical treatment for pseudobulbar affect. Its safety profile and diverse …

Acute ataxia in a pediatric patient poses a diagnostic dilemma for any physician. While the
most common etiologies are benign, occasional individuals require urgent intervention …

P2X receptors are cation channels that sense extracellular ATP. Many therapeutic
candidates targeting P2X receptors have begun clinical trials or acquired approval for the …

Initiation of ketamine use often occurs in adolescence, yet little is known about long-term
consequences when use begins in this developmental period. The current experiments …

Patients can use numerous drugs that exist outside of existing regulatory statutes in order to
get “legal highs.” Legal psychoactive substances represent a challenge to the emergency …

The glutamatergic system has emerged as a novel pathway for treating major depressive
disorder (MDD) with the focus on producing both rapid and sustained antidepressant effects …

Dextromethorphan (DXM) is a medication available in both prescription and non-
prescription over the counter (OTC) formulations and is utilized as an antitussant. DXM is …

Dextromethorphan (DXM), the methylated dextrorotatory analogue of a μ-opioid receptor
agonist, levorphanol, is a widely available antitussive medicine. At higher levels compared …

BACKGROUND Dextromethorphan is a prevalent antitussive agent that can be easily
obtained as an over-the-counter medication. There has been a growing number of reported …

INTRODUCTION ''Classic''toxidromes are a cornerstone of emergency medical education
(Table 1), yet a heterogeneous cluster of less understood recreational drug use among …