Rheumatoid arthritis (RA) is a multifactorial autoimmune disease of unknown etiology,
primarily affecting the joints, then extra-articular manifestations can occur. Due to its …

The adult skeleton regenerates by temporary cellular structures that comprise teams of
juxtaposed osteoclasts and osteoblasts and replace periodically old bone with new. A …

Network meta-analysis synthesizes direct and indirect evidence in a network of trials that
compare multiple interventions and has the potential to rank the competing treatments …

Background Biologics are used for the treatment of rheumatoid arthritis and many other
conditions. While the efficacy of biologics has been established, there is uncertainty …

Despite major progress in the treatment of rheumatoid arthritis (RA), strong unmet medical
need remains, as only a minor proportion of patients reach sustained clinical remission. New …

The association between chronic inflammation and increased risk of cardiovascular disease
in rheumatoid arthritis (RA) is well established. In the general population, inflammation is an …

Rheumatoid arthritis (RA), as a common chronic disease leading to severe disability,
requires early diagnosis and introduction of proper treatment. Deregulation in the cytokine …

Research into biomarkers of periodontitis is driven by mainly three targets: to identify 'at
risk'patients before periodontal tissue destruction occurs; to determine disease activity and …

Background Neovascular age‐related macular degeneration (AMD) is the leading cause of
legal blindness in elderly populations of industrialised countries. Bevacizumab (Avastin®) …

Objectives. To assess the proportion of RA patients who discontinued biologics in world
registries and health care databases and to identify causes and predictors of …