Estrogens and androgens in skeletal physiology and pathophysiology
M Almeida, MR Laurent, V Dubois… - Physiological …, 2017 - journals.physiology.org
Estrogens and androgens influence the growth and maintenance of the mammalian
skeleton and are responsible for its sexual dimorphism. Estrogen deficiency at menopause …
skeleton and are responsible for its sexual dimorphism. Estrogen deficiency at menopause …
Bone quality: the determinants of bone strength and fragility
H Fonseca, D Moreira-Gonçalves, HJA Coriolano… - Sports medicine, 2014 - Springer
Bone fragility is a major health concern, as the increased risk of bone fractures has
devastating outcomes in terms of mortality, decreased autonomy, and healthcare costs …
devastating outcomes in terms of mortality, decreased autonomy, and healthcare costs …
TBS (trabecular bone score) and diabetes-related fracture risk
Context: Type 2 diabetes is associated with increased fracture risk but paradoxically greater
bone mineral density (BMD). Trabecular bone score (TBS) is derived from the texture of the …
bone mineral density (BMD). Trabecular bone score (TBS) is derived from the texture of the …
FRAX underestimates fracture risk in patients with diabetes
The study objective was to determine whether diabetes is a risk factor for incident hip or
major osteoporotic fractures independent of the WHO fracture risk assessment tool (FRAX) …
major osteoporotic fractures independent of the WHO fracture risk assessment tool (FRAX) …
A decade of FRAX: how has it changed the management of osteoporosis?
The fracture risk assessment tool, FRAX®, was released in 2008 and provides country-
specific algorithms for estimating individualized 10-year probability of hip and major …
specific algorithms for estimating individualized 10-year probability of hip and major …
[HTML][HTML] Osteoporosis and osteoporotic fracture fact sheet in Korea
Background The socioeconomic burdens of osteoporosis and related fractures have
increased in parallel with population aging. The Korea Society of Bone and Mineral …
increased in parallel with population aging. The Korea Society of Bone and Mineral …
Comparison of methods for improving fracture risk assessment in diabetes: the Manitoba BMD registry
Type 2 diabetes is a risk factor for fracture independent of FRAX (fracture risk assessment)
probability. We directly compared four proposed methods to improve the performance of …
probability. We directly compared four proposed methods to improve the performance of …
Cortical bone porosity: what is it, why is it important, and how can we detect it?
DML Cooper, CE Kawalilak, K Harrison… - Current osteoporosis …, 2016 - Springer
There is growing recognition of the role of micro-architecture in osteoporotic bone loss and
fragility. This trend has been driven by advances in imaging technology, which have …
fragility. This trend has been driven by advances in imaging technology, which have …
[HTML][HTML] Circulating microRNAs as novel biomarkers for bone diseases–complex signatures for multifactorial diseases?
M Hackl, U Heilmeier, S Weilner, J Grillari - Molecular and cellular …, 2016 - Elsevier
Biomarkers are essential tools in clinical research and practice. Useful biomarkers must
combine good measurability, validated association with biological processes or outcomes …
combine good measurability, validated association with biological processes or outcomes …
The need to distinguish intervention thresholds and diagnostic thresholds in the management of osteoporosis
JA Kanis, EV McCloskey, NC Harvey, C Cooper… - Osteoporosis …, 2023 - Springer
This position paper of the International Osteoporosis Foundation (IOF) and the European
Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and …
Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and …
