The neuroimmune axis of Alzheimer's disease

M Jorfi, A Maaser-Hecker, RE Tanzi - Genome Medicine, 2023 - Springer
Alzheimer's disease (AD) is a genetically complex and heterogeneous disorder with
multifaceted neuropathological features, including β-amyloid plaques, neurofibrillary …

Psychiatric face of COVID-19

L Steardo Jr, L Steardo, A Verkhratsky - Translational psychiatry, 2020 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) represents a severe multiorgan
pathology which, besides cardio-respiratory manifestations, affects the function of the central …

A meta-analysis of cytokines in Alzheimer's disease

W Swardfager, K Lanctôt, L Rothenburg, A Wong… - Biological …, 2010 - Elsevier
BACKGROUND: Studies suggest that inflammation is involved in the neurodegenerative
cascade leading to Alzheimer's disease (AD) pathology and symptoms. This study sought to …

Microglia and neurodegeneration: the role of systemic inflammation

C Cunningham - Glia, 2013 - Wiley Online Library
It is well accepted that CNS inflammation has a role in the progression of chronic
neurodegenerative disease, although the mechanisms through which this occurs are still …

Human health risk assessment for aluminium, aluminium oxide, and aluminium hydroxide

D Krewski, RA Yokel, E Nieboer… - Journal of Toxicology …, 2007 - Taylor & Francis
Full article: Human Health Risk Assessment for Aluminium, Aluminium Oxide, and Aluminium
Hydroxide Skip to Main Content Taylor and Francis Online homepage Taylor and Francis …

Gram-negative bacterial molecules associate with Alzheimer disease pathology

X Zhan, B Stamova, LW Jin, C DeCarli, B Phinney… - Neurology, 2016 - AAN Enterprises
Objective: We determined whether Gram-negative bacterial molecules are associated with
Alzheimer disease (AD) neuropathology given that previous studies demonstrate Gram …

[HTML][HTML] Lipopolysaccharide associates with amyloid plaques, neurons and oligodendrocytes in Alzheimer's disease brain: a review

X Zhan, B Stamova, FR Sharp - Frontiers in aging neuroscience, 2018 - frontiersin.org
This review proposes that lipopolysaccharide (LPS, found in the wall of all Gram-negative
bacteria) could play a role in causing sporadic Alzheimer's disease (AD). This is based in …

Overwhelming evidence for a major role for herpes simplex virus type 1 (HSV1) in Alzheimer's disease (AD); underwhelming evidence against

RF Itzhaki - Vaccines, 2021 - mdpi.com
This review describes investigations of specific topics that lie within the general subject of
HSV1's role in AD/dementia, published in the last couple of years. They include studies on …

Targeting neuroinflammation to treat Alzheimer's disease

A Ardura-Fabregat, E Boddeke, A Boza-Serrano… - CNS drugs, 2017 - Springer
Over the past few decades, research on Alzheimer's disease (AD) has focused on
pathomechanisms linked to two of the major pathological hallmarks of extracellular …

Risk of Alzheimer's disease following influenza vaccination: a claims-based cohort study using propensity score matching

AS Bukhbinder, Y Ling, O Hasan… - Journal of …, 2022 - content.iospress.com
Background: Prior studies have found a reduced risk of dementia of any etiology following
influenza vaccination in selected populations, including veterans and patients with serious …