Randomized controlled trials often suffer from two major complications, ie, noncompliance
and missing outcomes. One potential solution to this problem is a statistical concept called …

Clinicians, institutions, and policy makers use results from randomized controlled trials to
make decisions regarding therapeutic interventions for their patients and populations …

Background The clinical effect of routine oxygen therapy in patients with suspected acute
myocardial infarction who do not have hypoxemia at baseline is uncertain. Methods In this …

Importance Myelofibrosis is a hematologic malignancy characterized by splenomegaly and
debilitating symptoms. Thrombocytopenia is a poor prognostic feature and limits use of …

Background Sensitivity analyses play a crucial role in assessing the robustness of the
findings or conclusions based on primary analyses of data in clinical trials. They are a critical …

Context: Various drugs affect body weight as a side effect. Objective: We conducted this
systematic review and meta-analysis to summarize the evidence about commonly …

OBJECTIVE—The purpose of this study was to evaluate safety and clinical efficacy of
negative pressure wound therapy (NPWT) compared with advanced moist wound therapy …

Background Use of pressure ulcer risk assessment tools or scales is a component of the
assessment process used to identify individuals at risk of developing a pressure ulcer. Use …

Research on bias in clinical trials may help identify some of the reasons why investigators
sometimes reach the wrong conclusions about intervention effects. Several quality …

Background: Arthroscopic hip surgery has risen 18-fold in the past decade; however, there is
a dearth of clinical trials comparing surgery with nonoperative management. Purpose: To …