Alcohol and hepatocellular carcinoma

H Matsushita, A Takaki - BMJ open gastroenterology, 2019 - bmjopengastro.bmj.com
Background Alcohol is classified as a Group 1 carcinogen by the International Agency for
Research on Cancer because it induces hepatocellular carcinoma (among other cancers) in …

The dynamic gastric environment and its impact on drug and formulation behaviour

J Van den Abeele, J Rubbens, J Brouwers… - European Journal of …, 2017 - Elsevier
Before being absorbed in the small intestine and/or colon, orally administered drugs
inevitably need to pass through the stomach. Hence, it seems reasonable that the residence …

Absorption and peak blood alcohol concentration after drinking beer, wine, or spirits

MC Mitchell Jr, EL Teigen… - Alcoholism: clinical and …, 2014 - Wiley Online Library
Background Both the amount and the rate of absorption of ethanol (EtOH) from alcoholic
beverages are key determinants of the peak blood alcohol concentration (BAC) and …

First pass metabolism of ethanol is strikingly influenced by the speed of gastric emptying

CM Oneta, UA Simanowski, M Martinez… - Gut, 1998 - gut.bmj.com
Background—Ethanol undergoes a first pass metabolism (FPM) in the stomach and liver.
Gastric FPM of ethanol primarily depends on the activity of gastric alcohol dehydrogenase …

Role of immunological cells in hepatocellular carcinoma disease and associated pathways

R Aasarey, K Yadav, BK Kashyap… - ACS Pharmacology & …, 2023 - ACS Publications
Hepatocellular carcinoma (HCC) remains one of the predominant causes of cancer-related
mortality across the globe. It is attributed to obesity, excessive alcohol consumption …

First‐pass metabolism of ethanol is predominantly gastric

RT Lim, RT Gentry, D Ito, H Yokoyama… - Alcoholism: Clinical …, 1993 - Wiley Online Library
Oral consumption of alcohol results in much lower blood alcohol concentrations (BACs) than
does the same dose administered intravenously, suggesting significant first‐pass …

[BOOK][B] Handbook of food-drug interactions

B McCabe-Sellers, EH Frankel, JJ Wolfe - 2003 - taylorfrancis.com
With contributions from the fields of pharmacy, dietetics, and medicine, Handbook of Food-
Drug Interactions serves as an interdisciplinary guide to the prevention and correction of …

Effects of multi-species probiotic supplementation on alcohol metabolism in rats

TJ Lim, S Lim, JH Yoon, MJ Chung - Journal of Microbiology, 2021 - Springer
Probiotics are known to protect against liver damage induced by the alcohol and
acetaldehyde accumulation associated with alcohol intake. However, there have been few …

Gastric emptying and gastrointestinal absorption of alcohol ingested with a meal

A Cortot, G Jobin, F Ducrot, C Aymes… - Digestive diseases and …, 1986 - Springer
We have measured, by an intubation method, gastric evacuation and gastrointestinal
absorption of alcohol ingested with a meal in seven healthy nonalcoholic subjects. A …

Cigarette smoking and rate of gastric emptying: effect on alcohol absorption.

RD Johnson, M Horowitz, AF Maddox, JM Wishart… - British Medical …, 1991 - bmj.com
OBJECTIVE--To examine the effects of cigarette smoking on alcohol absorption and gastric
emptying. DESIGN--Randomised crossover study. SETTING--Research project in …