Importance Harms and benefits of opioids for chronic noncancer pain remain unclear.
Objective To systematically review randomized clinical trials (RCTs) of opioids for chronic …

Objective To determine the benefits and harms of medical cannabis and cannabinoids for
chronic pain. Design Systematic review and meta-analysis. Data sources MEDLINE, EMBASE, …

Objective To assess the efficacy and harms of adding medical cannabis to prescription
opioids among people living with chronic pain. Design Systematic review. Data sources …

Extensive use of chromium (Cr) and arsenic (As) based preservatives from the leather
tanning industry in Pakistan has had a deleterious effect on the soils surrounding production …

Arsenic poisoning constitutes a major threat to humans, causing various health problems.
Almost everywhere across the world certain “hotspots” have been detected, putting in danger …

Bacterial transformation is a crucial part of cloning process and has been widely used in many
studies (Swords, 2003; Gigova et al., 2006). The mechanism is marked by two phases, the …

Carcinogenic effects of arsenic through consumption of contaminated water are an alarming
threat and there is an emergent need to reduce extremely high levels of toxic arsenic from …

Objective Approximately one in four total knee replacement patients develop persistent pain.
Identification of those at higher risk could help inform optimal management. Methods We …

Multidrug-resistant Klebsiella pneumoniae is a nosocomial pathogen, produces septicemia,
pneumonia and UTI. Excessive use of antibiotics contributes towards emergence of …

In recent decades, “contamination of the environment, food, and feed by different contaminants
such as heavy metals and toxins is increasing due to industrial life.” Commercial milk and …