Background: Because granulocyte colony-stimulating factor (G-CSF) has anti-inflammatory
and neuroprotective properties and is known to mobilize stem cells, it may be useful in the …

Background and Purpose—Granulocyte colony-stimulating factor (G-CSF) is a promising
stroke drug candidate. The present phase IIa study assessed safety and tolerability over a …

Background and Purpose—Granulocyte colony–stimulating factor (G-CSF; AX200;
Filgrastim) is a stroke drug candidate with excellent preclinical evidence for efficacy. A …

Background: Granulocyte-colony stimulating factor (G-CSF) shows promise as a treatment
for stroke. This systematic review assesses G-CSF in experimental ischaemic stroke …

Background and Purpose—Loss of motor function is common after stroke and leads to
significant chronic disability. Stem cells are capable of self-renewal and of differentiating into …

Background and Purpose—Granulocyte-colony stimulating factor (G-CSF) is neuroprotective
in experimental stroke and mobilizes CD34+ peripheral blood stem cells into the circulation …

The administration of CD34‐positive cells after stroke has been shown to have a beneficial
effect on functional recovery by accelerating angiogenesis and neurogenesis in rodent …

Background and Purpose—Recent reports have described the efficacy of the hematopoietic
growth factor granulocyte-colony stimulating factor (G-CSF) in animal stroke models. Early …

Recent studies have shown that administration of granulocyte colony‐stimulating factor (G‐
CSF) is neuroprotective. However, the precise mechanisms of the neuroprotective effect of G …

Background and Purpose—The potential neuroprotective effect of the granulocyte colony–
stimulating factor (G-CSF) after glutamate-induced excitotoxicity in cell culture and after focal …