Prevalence of genetic variants associated with inflammatory bowel disease in a healthy First Nations cohort

TB Murdoch, CN Bernstein, H El-Gabalawy… - Cmaj, 2012 - Can Med Assoc
Background: Inflammatory bowel disease is the result of both genes and environment.
Canadian First Nations people, despite living in a region with a high prevalence of …

Common NOD2 Risk Variants in African Americans with Crohn's Disease Are Due Exclusively to Recent Caucasian Admixture

O Adeyanju, DT Okou, C Huang… - Inflammatory bowel …, 2012 - academic.oup.com
Background Crohn's disease (CD) is highly heritable. NOD2 has emerged as the main
susceptibility gene among individuals of European ancestry; however, NOD2 does not …

Genetics of inflammatory bowel disease in Asia: systematic review and meta-analysis

SC Ng, KKF Tsoi, MA Kamm, B Xia, J Wu… - Inflammatory bowel …, 2012 - academic.oup.com
Background Inflammatory bowel diseases (IBD) result from an interaction between genetic
and environmental factors. Preliminary findings suggest that susceptibility genes differ …

Phenotypic and genotypic characteristics of inflammatory bowel disease in French Canadians: comparison with a large North American repository

M Bhat, GC Nguyen, P Pare, R Lahaie… - Official journal of the …, 2009 - journals.lww.com
OBJECTIVES: Phenotype characteristics of inflammatory bowel disease (IBD) may differ
significantly among ethnic subpopulations. The aim of this study was to characterize the IBD …

[HTML][HTML] Clinical predictors of inflammatory bowel disease in a genetically well-defined Caucasian population

ZM Kanaan, MR Eichenberger, S Ahmad… - Journal of negative …, 2012 - Springer
Background Crohn's disease (CD) and ulcerative colitis (UC), the two main types of
inflammatory bowel disease (IBD), are multifactorial conditions of unknown etiology. The …

[HTML][HTML] African ancestry proportion influences ileal gene expression in inflammatory bowel disease

A Mo, C Krishnakumar, D Arafat, T Dhere… - Cellular and …, 2020 - cmghjournal.org
The influence of ancestry on inflammatory bowel disease (IBD) susceptibility has recently
been examined via several large-scale genome-wide association studies, 1, 2 but the effects …

Genome-wide association study identifies African-specific susceptibility loci in African Americans with inflammatory bowel disease

SR Brant, DT Okou, CL Simpson, DJ Cutler… - Gastroenterology, 2017 - Elsevier
Background & Aims The inflammatory bowel diseases (IBD) ulcerative colitis (UC) and
Crohn's disease (CD) cause significant morbidity and are increasing in prevalence among …

Genetic characterization and influence on inflammatory bowel disease expression in a diverse Hispanic South Florida cohort

OM Damas, L Gomez, MA Quintero… - Clinical and …, 2017 - journals.lww.com
OBJECTIVES: Hispanics represent an understudied inflammatory bowel disease (IBD)
population. Prior studies examining genetic predisposition to IBD in Hispanics are limited. In …

Characterization of genetic loci that affect susceptibility to inflammatory bowel diseases in African Americans

C Huang, T Haritunians, DT Okou, DJ Cutler, ME Zwick… - Gastroenterology, 2015 - Elsevier
Background & Aims Inflammatory bowel disease (IBD) has familial aggregation in African
Americans (AAs), but little is known about the molecular genetic susceptibility. Mapping …

[HTML][HTML] Association of NOD2 and IL23R with inflammatory bowel disease in Puerto Rico

V Ballester, X Guo, R Vendrell, T Haritunians… - PLoS …, 2014 - journals.plos.org
The Puerto Rico population may be modeled as an admixed population with contributions
from three continents: Sub-Saharan Africa, Ancient America, and Europe. Extending the …