User profiles for Todd F. Hatchette

Todd Hatchette

Professor, Department of Pathology, Dalhousie University
Verified email at nshealth.ca
Cited by 5144

[HTML][HTML] Real-time PCR-based SARS-CoV-2 detection in Canadian laboratories

…, R Fattouh, R Garceau, G German, TF Hatchette… - Journal of Clinical …, 2020 - Elsevier
With emergence of pandemic COVID-19, rapid and accurate diagnostic testing is essential.
This study compared laboratory-developed tests (LDTs) used for the detection of SARS-CoV-…

Practical guidance for clinical microbiology laboratories: viruses causing acute respiratory tract infections

…, E Babady, CC Ginocchio, TF Hatchette… - Clinical microbiology …, 2018 - Am Soc Microbiol
Respiratory viral infections are associated with a wide range of acute syndromes and
infectious disease processes in children and adults worldwide. Many viruses are implicated in …

Influenza A virus inhibits cytoplasmic stress granule formation

DA Khaperskyy, TF Hatchette… - The FASEB …, 2012 - Wiley Online Library
An important component of the mammalian stress response is the reprogramming of
translation. A variety of stresses trigger abrupt polysome disassembly and the accumulation of …

Goat-associated Q fever: a new disease in Newfoundland.

TF Hatchette, RC Hudson, WF Schlech… - Emerging infectious …, 2001 - ncbi.nlm.nih.gov
In the spring of 1999 in rural Newfoundland, abortions in goats were associated with illness
in goat workers. An epidemiologic investigation and a serologic survey were conducted in …

Pseudomonas aeruginosa Community-Acquired Pneumonia in Previously Healthy Adults: Case Report and Review of the Literature

TF Hatchette, R Gupta, TJ Marrie - Clinical Infectious Diseases, 2000 - academic.oup.com
We report a case of rapidly fatal Pseudomonas aeruginosa community-acquired pneumonia
(CAP) in a previously healthy 67-year-old woman. Eleven published case reports of P. …

Global epidemiology of non-influenza RNA respiratory viruses: data gaps and a growing need for surveillance

…, WI Lipkin, SJ Drews, TF Hatchette… - The Lancet Infectious …, 2017 - thelancet.com
Together with influenza, the non-influenza RNA respiratory viruses (NIRVs), which include
respiratory syncytial virus, parainfluenza viruses, coronavirus, rhinovirus, and human …

Influenza a virus host shutoff disables antiviral stress-induced translation arrest

…, BP Johnston, P Anderson, TF Hatchette… - PLoS …, 2014 - journals.plos.org
Influenza A virus (IAV) polymerase complexes function in the nucleus of infected cells,
generating mRNAs that bear 5′ caps and poly(A) tails, and which are exported to the cytoplasm …

[HTML][HTML] A combined oropharyngeal/nares swab is a suitable alternative to nasopharyngeal swabs for the detection of SARS-CoV-2

…, J MacDonald, J Pettipas, TF Hatchette… - Journal of Clinical …, 2020 - Elsevier
Given the global shortage of nasopharyngeal (NP) swabs typically used for respiratory virus
detection, alternative collection methods were evaluated during the COVID-19 pandemic. …

Persistent functional decline following hospitalization with influenza or acute respiratory illness

…, JE McElhaney, J LeBlanc, TF Hatchette… - Journal of the …, 2021 - Wiley Online Library
Background/objectives Influenza is associated with significant morbidity and mortality,
particularly for older adults. Persistent functional decline following hospitalization has important …

The role of seroepidemiology in the comprehensive surveillance of vaccine-preventable diseases

SE Wilson, SL Deeks, TF Hatchette, NS Crowcroft - Cmaj, 2012 - Can Med Assoc
Serological surveillance (serosurveillance) provides estimates of population-level immunity
against vaccine-preventable diseases using cross-sectional studies of antibody prevalence. …