Radioimmunoassay of CSF for encephalitogenic basic protein: a diagnostic test for MS?

TA McPherson, A Gilpin, TP Seland - … Medical Association Journal, 1972 - ncbi.nlm.nih.gov
Competitive inhibition of binding between radioiodine-labelled encephalitogenic basic
protein from human myelin (125 I-HEProt) and normal human alpha-2 macroglobulin and …

Sensitization to myelin basic protein in attacks of multiple sclerosis: A preliminary report

W Sheremata, DD Wood, AA Moscarello… - Journal of the …, 1978 - Elsevier
Recent attempts to detect the presence of antibody to encephalitogenic basic protein in
multiple sclerosis have generally been unsuccessful. The utilization of a new system of …

Binding of encephalitogenic basic protein by serum α-globulins

TA McPherson, JJ Marchalonis, V Lennon - Immunology, 1970 - ncbi.nlm.nih.gov
The binding capacity of human and rabbit serum and serum fractions for [125 I]
encephalitogenic basic protein, extracted from human brain, were determined by gel …

Antibody to encephalitogenic basic protein in multiple sclerosis and other neurological diseases as measured by immune adherence

EA Caspary, ME Chambers - European Neurology, 1970 - karger.com
Materials and Methods Sera from 20 cases of acute MS, 8 of chronic MS and 32 patients
suffering from other neurological diseases were studied. The normal control group (24) …

Radioimmunological determination of myelin basic protein in the CSF of neurological patients

JM Matthieu, P Bürgisser - Protides of the biological fluids, 1983 - Elsevier
Myelin basic protein (MBP) was measured in cerebrospinal fluid (CSF) samples using a
specific and sensitive radioimmunoassay (1.5 to 2.5 ng/ml). A moderate non-parallelism …

Detection of antibodies to the basic protein of human myelin by radioimmunoassay and immunofluorescence

VA Lennon, S Whittingham, PR Carnegie… - The Journal of …, 1971 - journals.aai.org
Specific antibodies to a basic protein that is a component of myelin were demonstrated
quantitatively by gel filtration radioimmunoassay in three species, rabbit, guinea pig and rat …

Purification of fully active human encephalitogenic basic protein on sulfoethyl-sephadex

MA Barton, TA McPherson… - Canadian Journal of …, 1972 - cdnsciencepub.com
Human encephalitogenic basic protein (HEP) was obtained in high yield after
chromatography on sulfoethyl-Sephadex C-50 (SE-Sephadex). The protein was shown to be …

Binding of 125I myelin basic protein by serum and cerebrospinal fluid

V Lennon, IR Mackay - Clinical and Experimental Immunology, 1972 - ncbi.nlm.nih.gov
A sensitive gel filtration redioimmunoassay was used to test for antibodies to the basic
protein of myelin, the antigen of experimental autoimmune encephalomyelitis, in serum and …

Myelin basic protein in CSF and blood: relationship between its presence and the occurrence of a destructive process in the brains of encephalitic patients

C Jacque, A Delassalle, G Rancurel… - Archives of …, 1982 - jamanetwork.com
• Serum and CSF levels of myelin basic protein (MBP) were measured in 50 patients with
encephalitis of various origins and severity. In nearly 50%, the CSF samples were found to …

Immuno-electron microscopic localization of the encephalitogenic basic protein in myelin

RM Herndon, HC Rauch… - Immunological …, 1973 - Taylor & Francis
Immuno-electron microscopic studies of the localization of encephalitogenic basic protein
demonstrate its presence in the major dense line of the myelin sheath. Staining could only …