Background The current practice of removing adenomatous polyps of the colon and rectum
is based on the belief that this will prevent colorectal cancer. To address the hypothesis that …

Adenomatous polyps are the most common neoplastic findings discovered in people who
undergo colorectal screening or who have a diagnostic work-up for symptoms. It was common …

Background The identification and removal of adenomatous polyps and post-polypectomy
surveillance are considered to be important for the control of colorectal cancer. In current …

Background In the National Polyp Study (NPS), colorectal cancer was prevented by colonoscopic
removal of adenomatous polyps. We evaluated the long-term effect of colonoscopic …

Background After patients have undergone colonoscopic polypectomy, it is uncertain
whether colonoscopic examination or a barium enema is the better method of surveillance. …

Background The adenoma–adenocarcinoma sequence in colorectal cancer suggests an
increased risk of colorectal cancer in the families of patients with adenomatous polyps. …

The adenoma-carcinoma sequence is now well established as the major pathway for the
development of colorectal cancer. 38 The natural history of this sequence is believed to evolve …

The National Polyp Study (NPS), a randomized clinical trial to evaluate effective surveillance
of patients discovered to have one or more colorectal adenomas, was the framework for this …

In the United States, colorectal cancer (CRC) is the third most common cancer diagnosed
among men and women and the second leading cause of death from cancer. CRC largely can …

… SJ Winawer …