Fetal exposure to nonsteroidal anti-inflammatory drugs and spontaneous abortions

S Daniel, G Koren, E Lunenfeld, N Bilenko, R Ratzon… - Cmaj, 2014 - Can Med Assoc
Background: Spontaneous abortion is the most common complication of pregnancy. Non-
steroidal anti-inflammatory drugs (NSAIDs) are widely used during pregnancy. Published …

Periconceptional over-the-counter nonsteroidal anti-inflammatory drug exposure and risk for spontaneous abortion

DRV Edwards, T Aldridge, DD Baird… - Obstetrics & …, 2012 - journals.lww.com
OBJECTIVE: To estimate the association between over-the-counter nonsteroidal anti-
inflammatory drug (NSAID) exposure during the early first trimester and risk for spontaneous …

[HTML][HTML] Use of nonaspirin nonsteroidal anti-inflammatory drugs during pregnancy and the risk of spontaneous abortion

HR Nakhai-Pour, P Broy, O Sheehy, A Bérard - Cmaj, 2011 - Can Med Assoc
Background: The association between the use of nonaspirin nonsteroidal anti-inflammatory
drugs (NSAIDs) during pregnancy and the risk of spontaneous abortion remains unclear …

Exposure to non-steroidal anti-inflammatory drugs during pregnancy and risk of miscarriage: population based cohort study

DK Li, L Liu, R Odouli - Bmj, 2003 - bmj.com
Objective To evaluate whether prenatal use of non-steroidal anti-inflammatory drugs
(NSAIDs) is associated with increased risk of miscarriage. Design Population based cohort …

Exposure to cox-2 inhibitors (coxibs) during the first trimester and pregnancy outcome: a prospective observational cohort study

K Dathe, S Padberg, S Hultzsch, LM Köhler… - European journal of …, 2018 - Springer
Abstract Purpose Cox-2-inhibitors (coxibs) are not recommended in pregnancy but early
exposure may occur, for instance in unplanned pregnancies. Experience in pregnancy is …

Maternal non-steroidal anti-inflammatory drug exposure during pregnancy and risk of miscarriage: a systematic review and meta-analysis

X Ying, D Bao, H Jiang, Y Shi - European Journal of Clinical …, 2022 - Springer
Background Numerous studies have suggested that non-steroidal anti-inflammatory drugs
(NSAIDs) might be associated with increased risk of miscarriage. However, these results are …

Immortal time bias in drug safety cohort studies: spontaneous abortion following nonsteroidal antiinflammatory drug exposure

S Daniel, G Koren, E Lunenfeld, A Levy - American Journal of Obstetrics …, 2015 - Elsevier
Objective Experimental research of drug safety in pregnancy is generally not feasible
because of ethical issues. Therefore, most of the information about drug safety in general …

Risk of preterm birth following late pregnancy exposure to NSAIDs or COX-2 inhibitors

A Bérard, O Sheehy, S Girard, JP Zhao, S Bernatsky - Pain, 2018 - journals.lww.com
Pregnant women may take nonsteroidal antiinflammatory drugs (NSAIDs), selective
cyclooxygenase (COX)-2 inhibitors, or biological agents to relieve symptoms or manage …

Exposure to non-steroidal anti-inflammatory drugs during pregnancy and the risk of selected birth defects: a prospective cohort study

MMHJ van Gelder, N Roeleveld, H Nordeng - PloS one, 2011 - journals.plos.org
Background Since use of non-steroidal anti-inflammatory drugs (NSAIDs) during pregnancy
is common, small increases in the risk of birth defects may have significant implications for …

Major malformations following exposure to nonsteroidal antiinflammatory drugs during the first trimester of pregnancy

S Daniel, I Matok, R Gorodischer, G Koren… - The Journal of …, 2012 - jrheum.org
Objective. Nonsteroidal antiinflammatory drugs (NSAID) are among the most common
medicines used by pregnant women. Published data are controversial regarding fetal safety …