User profiles for Ruth Frikke-Schmidt
Ruth Frikke-SchmidtCopenhagen University Hospital, Rigshospitalet and University of Copenhagen Verified email at regionh.dk Cited by 24372 |
LCAT, HDL cholesterol and ischemic cardiovascular disease: a Mendelian randomization study of HDL cholesterol in 54,500 individuals
…, BG Nordestgaard, R Frikke-Schmidt - The Journal of …, 2012 - academic.oup.com
Background: Epidemiologically, high-density lipoprotein (HDL) cholesterol levels associate
inversely with risk of ischemic cardiovascular disease. Whether this is a causal relation is …
inversely with risk of ischemic cardiovascular disease. Whether this is a causal relation is …
[HTML][HTML] Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
…, GM Peloso, M Orho-Melander, R Frikke-Schmidt… - The Lancet, 2012 - thelancet.com
Background High plasma HDL cholesterol is associated with reduced risk of myocardial
infarction, but whether this association is causal is unclear. Exploiting the fact that genotypes are …
infarction, but whether this association is causal is unclear. Exploiting the fact that genotypes are …
Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease
AB Jørgensen, R Frikke-Schmidt… - … England Journal of …, 2014 - Mass Medical Soc
Background High plasma levels of nonfasting triglycerides are associated with an increased
risk of ischemic cardiovascular disease. Whether lifelong low levels of nonfasting …
risk of ischemic cardiovascular disease. Whether lifelong low levels of nonfasting …
Rare and low-frequency coding variants alter human adult height
…, I Ford, M Fornage, PW Franks, R Frikke-Schmidt… - Nature, 2017 - nature.com
Height is a highly heritable, classic polygenic trait with approximately 700 common associated
variants identified through genome-wide association studies so far. Here, we report 83 …
variants identified through genome-wide association studies so far. Here, we report 83 …
Modeling of waning immunity after SARS-CoV-2 vaccination and influencing factors
…, MAH Larsen, SR Ostrowski, R Frikke-Schmidt… - Nature …, 2022 - nature.com
SARS-CoV-2 vaccines are crucial in controlling COVID-19, but knowledge of which factors
determine waning immunity is limited. We examined antibody levels and T-cell gamma-…
determine waning immunity is limited. We examined antibody levels and T-cell gamma-…
Remnant cholesterol as a causal risk factor for ischemic heart disease
…, AB Jørgensen, R Frikke-Schmidt… - Journal of the American …, 2013 - jacc.org
Objectives : The aim of this study was to test the hypothesis that elevated nonfasting remnant
cholesterol is a causal risk factor for ischemic heart disease independent of reduced high-…
cholesterol is a causal risk factor for ischemic heart disease independent of reduced high-…
Exome-wide association study of plasma lipids in> 300,000 individuals
…, PW Franks, TM Frayling, R Frikke-Schmidt… - Nature …, 2017 - nature.com
We screened variants on an exome-focused genotyping array in> 300,000 participants (replication
in> 280,000 participants) and identified 444 independent variants in 250 loci …
in> 280,000 participants) and identified 444 independent variants in 250 loci …
Association of loss-of-function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease
R Frikke-Schmidt, BG Nordestgaard, MCA Stene… - Jama, 2008 - jamanetwork.com
Context Low levels of high-density lipoprotein (HDL) cholesterol are inversely related to
cardiovascular risk. Whether this is a causal effect is unclear. Objective To determine whether …
cardiovascular risk. Whether this is a causal effect is unclear. Objective To determine whether …
Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction
AB Jørgensen, R Frikke-Schmidt, AS West… - European heart …, 2013 - academic.oup.com
Aims Elevated non-fasting triglycerides mark elevated levels of remnant cholesterol. Using
a Mendelian randomization approach, we tested whether genetically increased remnant …
a Mendelian randomization approach, we tested whether genetically increased remnant …
[HTML][HTML] Oxygen targets in comatose survivors of cardiac arrest
…, M Frydland, RP Beske, R Frikke-Schmidt… - … England Journal of …, 2022 - Mass Medical Soc
Background The appropriate oxygenation target for mechanical ventilation in comatose survivors
of out-of-hospital cardiac arrest is unknown. Methods In this randomized trial with a 2-by…
of out-of-hospital cardiac arrest is unknown. Methods In this randomized trial with a 2-by…