Recipient and donor outcomes after living-donor liver transplant for unresectable colorectal liver metastases

R Hernandez-Alejandro, LI Ruffolo, K Sasaki… - JAMA …, 2022 - jamanetwork.com
Importance Colorectal cancer is a leading cause of cancer-related death, and nearly 70% of
patients with this cancer have unresectable colorectal cancer liver metastases (CRLMs). …

Early survival and safety of ALPPS: first report of the International ALPPS Registry

…, M Machado, R Hernandez-Alejandro… - Annals of …, 2014 - journals.lww.com
Objectives: To assess safety and outcomes of the novel 2-stage hepatectomy, Associating
Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS), using an …

ALPPS offers a better chance of complete resection in patients with primarily unresectable liver tumors compared with conventional‐staged hepatectomies: results of a …

…, K Croome, R HernandezAlejandro… - World journal of …, 2014 - Wiley Online Library
Background Portal vein occlusion to increase the size of the future liver remnant (FLR) is well
established, using portal vein ligation (PVL) or embolization (PVE) followed by resection 4–…

Can we improve the morbidity and mortality associated with the associating liver partition with portal vein ligation for staged hepatectomy (ALPPS) procedure in the …

R Hernandez-Alejandro, KA Bertens, K Pineda-Solis… - Surgery, 2015 - Elsevier
Background Meticulous selection of patients who can undergo the associating liver partition
with portal vein ligation for staged hepatectomy (ALPPS) procedure safely will be paramount …

Prediction of mortality after ALPPS stage-1: an analysis of 320 patients from the international ALPPS registry

…, EK Abdalla, R Hernandez-Alejandro… - Annals of …, 2015 - journals.lww.com
Objectives: The aim of this study was to identify predictors of 90-day mortality after Associating
Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS), available after …

[PDF][PDF] Total tumor volume and alpha‐fetoprotein for selection of transplant candidates with hepatocellular carcinoma: A prospective validation

C Toso, G Meeberg, R HernandezAlejandro… - …, 2015 - Wiley Online Library
The selection of liver transplantation (LT) candidates with hepatocellular carcinoma (HCC)
is currently validated based on Milan criteria. The use of extended criteria has remained a …

Defining benchmarks in liver transplantation: a multicenter outcome analysis determining best achievable results

…, M De Oliveira, R Hernandez-Alejandro… - Annals of …, 2018 - journals.lww.com
This multicentric study of 17 high-volume centers presents 12 benchmark values for liver
transplantation. Those values, mostly targeting markers of morbidity, were gathered from 2024 “…

First long-term oncologic results of the ALPPS procedure in a large cohort of patients with colorectal liver metastases

…, M Malagó, R Hernandez-Alejandro… - Annals of …, 2020 - journals.lww.com
Objectives: To analyze long-term oncological outcome along with prognostic risk factors in a
large cohort of patients with colorectal liver metastases (CRLM) undergoing ALPPS. …

MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their …

…, JK McCormick, O Lantz, R Hernandez-Alejandro… - PLoS …, 2017 - journals.plos.org
Superantigens (SAgs) are potent exotoxins secreted by Staphylococcus aureus and Streptococcus
pyogenes. They target a large fraction of T cell pools to set in motion a “cytokine storm…

[HTML][HTML] High mortality after ALPPS for perihilar cholangiocarcinoma: case-control analysis including the first series from the international ALPPS registry

…, BG Koerkamp, M Malago, R Hernandez-Alejandro… - HPB, 2017 - Elsevier
Introduction Resection of perihilar cholangiocarcinoma (PHC) entails high-risk surgery with
postoperative mortality reported up to 18%, even in specialized centers. The aim of this study …