The production of most toxins and other exoproteins in Staphylococcus aureus is controlled
globally by a complex polycistronic regulatory locus, agr. Secretory proteins are up‐…

The accessory genes of Staphylococcus aureus, in‐cluding those involved in pathogenesis,
are controlled by a complex regulatory network that includes at least four two‐component …

Toxic shock syndrome (TSS) is a complex of generalized symptoms caused by a local
staphylococcal infection, and a circulating toxin is thought to be involved. Indeed, nearly 100% of …

The synthesis of virulence factors and other extracellular proteins by Staphylococcus aureus
is globally controlled by theagr locus, which encodes a two-component signaling pathway …

Plasmid Replicon A bacterial plasmid is a species of nonessential extra-chromosomal
deoxyribonucleic acid (DNA) that replicates autonomously as a stable component of the cell's …

The staphylococcal agr locus encodes a quorum sensing (QS) system that controls the
expression of virulence and other accessory genes by a classical two-component signaling …

Background The relative benefits and risks of performing coronary-artery bypass grafting (CABG)
with a beating-heart technique (off-pump CABG), as compared with cardiopulmonary …

BACKGROUND: Cerebral deoxygenation is associated with various adverse systemic
outcomes. We hypothesized, by using the brain as an index organ, that interventions to improve …

Some bacterial pathogens elaborate and secrete virulence factors in response to environmental
signals, others in response to a specific host product, and still others in response to no …

A high-frequency transducing element for erythromycin resistance in Staphylococcus aureus
has been found. This element, P11de, is apparently the result of a recombinational event …