[HTML][HTML] Tumour necrosis factor-α inhibitors and the reactivation of latent tuberculosis infection

R Long, M Gardam - Cmaj, 2003 - Can Med Assoc
Fig. 1: The putative role of tumour necrosis factor-α (TNF-α) in the cell-mediated normal
human immune response to tuberculosis infection. The macrophage (A) phagocytoses the …

[HTML][HTML] Tumor necrosis factor is critical to control tuberculosis infection

M Jacobs, D Togbe, C Fremond, A Samarina… - Microbes and …, 2007 - Elsevier
Tumor necrosis factor (TNF) is critical and non-redundant to control Mycobacterium
tuberculosis infection and cannot be replaced by other proinflammatory cytokines …

How tumour necrosis factor blockers interfere with tuberculosis immunity

J Harris, J Keane - Clinical & Experimental Immunology, 2010 - academic.oup.com
Tumour necrosis factor (TNF) is a potent inflammatory cytokine that plays an important role
in immunity to numerous bacterial infections, including Mycobacterium tuberculosis (Mtb) …

Reactivation of tuberculosis by tumor necrosis factor neutralization

M Jacobs, A Samarina, S Grivennikov, T Botha… - European cytokine …, 2007 - jle.com
Tumor necrosis factor (TNF) is required in the control of infection with Mycobacterium
tuberculosis (Mtb), the causative agent of tuberculosis. TNF is essential and non-redundant …

Immunological control of tuberculosis: role of tumour necrosis factor and more

S Stenger - Annals of the rheumatic diseases, 2005 - ard.bmj.com
Therapy of autoimmune diseases with tumour necrosis factor (TNF) neutralising agents has
provided a unique opportunity to learn about the significance of TNF in the maintenance of …

Neutralization of tumor necrosis factor (TNF) by antibody but not TNF receptor fusion molecule exacerbates chronic murine tuberculosis

HL Plessner, PL Lin, T Kohno, JS Louie… - The Journal of …, 2007 - academic.oup.com
Tumor necrosis factor (TNF) plays an essential role in the immunologic maintenance of
Mycobacterium tuberculosis infection. Although an increased rate of tuberculosis has been …

Tumor-necrosis-factor blockers: differential effects on mycobacterial immunity

OY Saliu, C Sofer, DS Stein… - The Journal of …, 2006 - academic.oup.com
Background Tumor necrosis factor (TNF) plays a pathogenic role in rheumatoid arthritis but
is essential for antimycobacterial host defenses. The risk of reactivation of latent …

Tumor Necrosis Factor Blockers Influence Macrophage Responses to Mycobacterium tuberculosis

J Harris, JC Hope, J Keane - The Journal of infectious diseases, 2008 - academic.oup.com
Tumor necrosis factor (TNF)-α is a proinflammatory cytokine that mediates inflammation in
response to various pathogens, including Mycobacterium tuberculosis, but is also a key …

Risk and prevention of tuberculosis and other serious opportunistic infections associated with the inhibition of tumor necrosis factor

KL Winthrop - Nature clinical practice Rheumatology, 2006 - nature.com
Tumor necrosis factor (TNF) is a proinflammatory cytokine that has a key role in the
pathogenesis of a variety of autoimmune diseases—including rheumatoid arthritis—and is …

[HTML][HTML] Tumor necrosis factor neutralization combined with chemotherapy enhances Mycobacterium tuberculosis clearance and reduces lung pathology

ML Bourigault, R Vacher, S Rose… - American journal of …, 2013 - ncbi.nlm.nih.gov
Tuberculosis (TB) is a major health problem requiring sustained immunity to inhibit
Mycobacterium tuberculosis growth and appropriate antimicrobial therapy to prevent …