Correlation of healing capacity with vascular response in the anterior cruciate and medial collateral ligaments of the rabbit

RC Bray, CA Leonard, PT Salo - Journal of orthopaedic …, 2003 - Wiley Online Library
In clinical terms, functional recovery after anterior cruciate ligament (ACL) injury is generally
poorer than after medial collateral ligament (MCL) injury. In experimental studies of injury, …

Vascular physiology and long‐term healing of partial ligament tears

RC Bray, CA Leonard, PT Salo - Journal of Orthopaedic …, 2002 - Wiley Online Library
Functional outcomes of anterior cruciate ligament (ACL) injury are generally poorer than
those of medial collateral ligament (MCL) tears. Following ligament damage, all phases of …

Neuronal pathways in tendon healing and tendinopathy: update

…, SL Franklin, BJF Dean, AJ Carr, PT Salo… - 2016 - openarchive.ki.se
The regulatory mechanisms involved in tendon homeostasis and repair are not fully
understood. Accumulating data, however, demonstrate that the nervous system, in addition to …

[HTML][HTML] Synovial mesenchymal progenitor derived aggrecan regulates cartilage homeostasis and endogenous repair capacity

…, C Leonard, M Kapoor, JR Matyas, PT Salo - Cell Death & …, 2022 - nature.com
Aggrecan is a critical component of the extracellular matrix of all cartilages. One of the early
hallmarks of osteoarthritis (OA) is the loss of aggrecan from articular cartilage followed by …

The mast cell stabilizer ketotifen reduces joint capsule fibrosis in a rabbit model of post-traumatic joint contractures

MJ Monument, DA Hart, AD Befus, PT Salo… - Inflammation …, 2012 - Springer
Objectives Using a rabbit model of post-traumatic joint contractures, we investigated
whether treatment with a mast cell stabilizer after joint injury would lessen the molecular …

Vascular response of the meniscus to injury: effects of immobilization

…, CA Leonard, CA Sutherland, PT Salo - Journal of …, 2001 - Wiley Online Library
Failed meniscal healing may lead to degenerative osteoarthritis of the knee. Healing is thought
to be dependent upon an adequate blood supply, yet “normal” vascular changes during …

Selective joint denervation promotes knee osteoarthritis in the aging rat

PT Salo, T Hogervorst, RA Seerattan… - Journal of …, 2002 - Wiley Online Library
Osteoarthritis is the most common joint disorder with aging, but its cause is unknown. Mice
lose joint afferents with aging, and this loss precedes development of osteoarthritis. We …

The mast cell stabilizer ketotifen fumarate lessens contracture severity and myofibroblast hyperplasia: a study of a rabbit model of posttraumatic joint contractures

MJ Monument, DA Hart, AD Befus, PT Salo, M Zhang… - JBJS, 2010 - journals.lww.com
Background: The propensity of joints to become stiff after trauma is widely appreciated, and
the joint capsule is commonly recognized as the major motion-limiting anatomical structure. …

Posttraumatic elbow contractures: targeting neuroinflammatory fibrogenic mechanisms

MJ Monument, DA Hart, PT Salo, KA Hildebrand… - Journal of Orthopaedic …, 2013 - Elsevier
Posttraumatic elbow stiffness remains a common and challenging clinical problem. In the
setting of a congruent articular surface, the joint capsule is regarded as the major motion-…

[DOC][DOC] Neuronal pathways in tendon healing

PW Ackermann, PT Salo, DA Hart - Front Biosci, 2009 - researchgate.net
1. ABSTRACT The regulatory mechanisms involved in tendon homeostasis and repair are
not fully understood. Accumulating data, however, demonstrate that the nervous system, in …