Background VTE is a common cause of preventable death in surgical patients. Methods We
developed recommendations for thromboprophylaxis in nonorthopedic surgical patients by …

Blinding refers to the concealment of group allocation from one or more individuals involved
in a clinical research study, most commonly a randomized controlled trial (RCT). Although …

Importance Ablative therapies extend the capability of delivering potentially curative
treatment for bilateral hepatic colorectal metastases. Objective To compare the long-term …

Objective To investigate the association between treatment induced change in high density
lipoprotein cholesterol and total death, coronary heart disease death, and coronary heart …

Presenting continuous outcomes in Summary of Findings tables presents particular challenges
to interpretation. When each study uses the same outcome measure, and the units of that …

Background: Gastrectomy remains a major operation with potential for significant deterioration
in patients' health-related quality of life (QOL). This study assessed differences in QOL …

Objective: To determine the impact of prophylactic corticosteroid administration on
postoperative nausea, vomiting, pain and complications in patients undergoing laparoscopic …

Methodologists have traditionally categorized randomized controlled trials (RCTs) as
explanatory (representing the ideal setting) and pragmatic (representing the real-world setting). …

Applies to: Patients with acute stroke or myocardial infarction 1 00 99 98 97 96 95 94 93 92
91 90 89 88 87 Recommendation 1 Stop oxygen therapy no higher than 96% saturation …

Instruments that are useful in clinical or research practice will, when the object of measurement
is stable, yield similar results when applied at different times, in different situations, or by …