Objectives: Debate continues with respect to a “watch and wait” approach versus immediate
antibiotic treatment for the initial treatment of acute otitis media. In this double-blind …

Background Recommendations vary regarding immediate antimicrobial treatment versus
watchful waiting for children younger than 2 years of age with acute otitis media. Methods …

Background The efficacy of antimicrobial treatment in children with acute otitis media
remains controversial. Methods In this randomized, double-blind trial, children 6 to 35 …

Background 10 days of amoxicillin/clavulanic acid high dose and 5 days of cefdinir have
been the preferred first-or second-line antibiotics for treatment of children with acute otitis …

Objectives The objective of the study was to compare the antibiotic treatment failure and
recurrence rates between antibiotic agents (amoxicillin, amoxicillin-clavulanate, cefdinir, and …

Background: All but 2 of the 15 published trials have failed to show a difference in efficacy
between short (3 to 5 days) and standard (7 to 10 days) antibiotic regimens for acute otitis …

Objective.—To conduct a meta-analysis of randomized controlled trials of antibiotic
treatment of acute otitis media in children to determine whether outcomes were comparable …

OBJECTIVE: To compare 5-, 7-and 10-day duration of antibiotic therapy for acute otitis
media (AOM) in children. STUDY DESIGN AND SETTING: Prospective nonrandomized 1 …

Objective. The widespread use of antibiotics for treatment of acute otitis media (AOM) has
resulted in the emergence of multidrug-resistant pathogens that are difficult to treat …

Context. In 1995,> 5 million episodes of acute otitis media (AOM) accounted for $3 billion in
health care expenditures. Objectives. To synthesize the literature on the natural history of …