Purpose The phase III PROCLAIM study evaluated overall survival (OS) of concurrent
pemetrexed-cisplatin and thoracic radiation therapy (TRT) followed by consolidation pemetrexed, …

The authors examined the role of systemic adjuvant therapy in patients with high‐risk, resected,
primary melanoma. Outcomes of interest included overall survival, disease‐free survival, …

PURPOSE We designed and conducted a randomized, double-blind, placebo-controlled
trial to compare the response rates and survival of patients with metastatic melanoma who …

Although the Breslow measurement of tumor thickness of melanoma is the most significant
predictor of survival, the biologic behavior of thick lesions remains unpredictable. MIB-1, a …

Background. Extragonadal germ cell tumors (EGCT) represent only 2–5% of adult germ cell
malignancies. Because they are rare and biologically distinct from testis cancer, their natural …

This clinical trial summary provides the background and rationale for a randomized trial
examining the benefits of pemetrexed/cisplatin chemotherapy combined with radiation followed …

Study Objective: To determine the feasibility and safety of outpatient continuous narcotic
infusions with additional bolus capabilities (patient-controlled analgesia) in patients with cancer …

Purpose Chemoradiation therapy trials of different tumors, including lung cancer, have
shown a correlation between protocol deviations and adverse outcomes. Radiation therapy …

Purpose: The therapeutic effectiveness of cancer vaccines, composed of tumor antigens
that are also self-antigens, may be limited by the normal mechanisms that preserve …

BACKGROUND The route of administration and extent of helper T‐cell activation are factors
that are likely to be important for the development of effective cancer vaccines. In order to …