Bupropion abuse and overdose

N Stall, J Godwin, D Juurlink - Cmaj, 2014 - Can Med Assoc
Bupropion is used widely as a smoking cessation aid and antidepressant and is available in
immediate-and extendedrelease preparations. It blocks neuronal reuptake of dopamine and …

Intravenous bupropion: a previously undocumented method of abuse of a commonly prescribed antidepressant agent

D Baribeau, KF Araki - Journal of addiction medicine, 2013 - journals.lww.com
Bupropion is an antidepressant commonly prescribed as a smoking cessation aid. It has
effects on dopamine and norepinephrine, and can lower seizure threshold, particularly in …

Bupropion injection resulting in tissue necrosis and psychosis: previously undocumented complications of intravenous bupropion use disorder

M Strike, S Hatcher - Journal of addiction medicine, 2015 - journals.lww.com
Discussion: Bupropion seems to have addictive effects, particularly when administered
intravenously or intranasally. Individuals who inject high doses of bupropion may be at risk …

Bupropion: risks and benefits

S Ross, D Williams - Expert opinion on drug safety, 2005 - Taylor & Francis
Cigarette smoking represents one of the most preventable causes of death worldwide.
However, success rates for stopping smoking are disappointingly low and are associated …

Bupropion for the treatment of tobacco dependence: guidelines for balancing risks and benefits

JT Hays, JO Ebbert - CNS drugs, 2003 - Springer
Tobacco use, particularly cigarette smoking, is now a global pandemic. The expected
morbidity and mortality from smoking-attributable diseases will continue to rise for the next …

Bupropion: a review of its use in the management of smoking cessation

KJ Holm, CM Spencer - Drugs, 2000 - Springer
Sustained release bupropion (amfebutamone) is a non-nicotine agent that is indicated as an
aid to smoking cessation. In 2 large well designed clinical trials, sustained release …

15 years of clinical experience with bupropion HCl: from bupropion to bupropion SR to bupropion XL

M Fava, AJ Rush, ME Thase, A Clayton… - … care companion to …, 2005 - psychiatrist.com
Background: Bupropion has been available in the United States since 1989. Initially a
thricedaily immediate-release formulation, a twicedaily sustained-release formulation …

Systematic review of preclinical, clinical, and post-marketing evidence of bupropion misuse potential

AC Naglich, ES Brown, B Adinoff - The American journal of drug …, 2019 - Taylor & Francis
Background: Bupropion is a substituted cathinone compound widely used as a first line or
add-on treatment for depression, smoking cessation, and more recently in combination with …

Review of bupropion for smoking cessation

R Richmond, N Zwar - Drug and alcohol review, 2003 - Taylor & Francis
The advent of bupropion hydrochloride sustained release (Zyban) has heralded a major
change in the options available for smoking cessation pharmacotherapy. Bupropion is a …

Clinical characteristics and outcomes associated with bupropion overdose: a Canadian perspective

E Stewart, K Grewal, H Hudson, M Thompson… - Clinical …, 2020 - Taylor & Francis
Background: Therapeutic use, overdose and recreational abuse of bupropion are
increasing. The purpose of this study was to describe the incidence and outcomes of …