Probiotic therapy for the prevention and treatment of Clostridium difficile-associated diarrhea: a systematic review

N Dendukuri, V Costa, M McGregor, JM Brophy - Cmaj, 2005 - Can Med Assoc
Background: The recent increase in the number and severity of cases of nosocomial
Clostridium difficile-associated diarrhea (CDAD) has prompted interest in the use of …

Probiotics for the Prevention of Clostridium difficile–Associated Diarrhea: A Systematic Review and Meta-analysis

BC Johnston, SSY Ma, JZ Goldenberg… - Annals of internal …, 2012 - acpjournals.org
Background: Antibiotic treatment may disturb the resistance of gastrointestinal flora to
colonization. This may result in complications, the most serious of which is Clostridium …

Probiotics are effective at preventing Clostridium difficile-associated diarrhea: a systematic review and meta-analysis

CSM Lau, RS Chamberlain - International journal of general …, 2016 - Taylor & Francis
Introduction Clostridium difficile infection (CDI) is the leading cause of antibiotic-associated
diarrhea. CDI has increased in incidence and severity over the past decade, and is a …

Which probiotic has the best effect on preventing Clostridium difficile‐associated diarrhea? A systematic review and network meta‐analysis

Y Ma, JY Yang, X Peng, KY Xiao, Q Xu… - Journal of Digestive …, 2020 - Wiley Online Library
Objective Clostridium difficile‐associated diarrhea (CDAD) accounts for up to 25% of
patients with antibiotic‐associated diarrhea (AAD). We aimed to determine which probiotic is …

Probiotics for Clostridium difficile–associated diarrhea: focus on Lactobacillus rhamnosus GG and Saccharomyces boulardii

M Segarra-Newnham - Annals of Pharmacotherapy, 2007 - journals.sagepub.com
Objective: To review the literature on the use of probiotics to treat or prevent recurrences of
Clostridium difficile-associated diarrhea (CDAD) by replacing normal gastric flora. Data …

Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease

LV McFarland - Official journal of the American College of …, 2006 - journals.lww.com
Meta-Analysis of Probiotics for the Prevention of Antibiotic... : Official journal of the American
College of Gastroenterology | ACG Meta-Analysis of Probiotics for the Prevention of Antibiotic …

Probiotics for the prevention of Clostridium difficile‐associated diarrhea in adults and children

JZ Goldenberg, C Yap, L Lytvyn… - Cochrane Database …, 2017 - cochranelibrary.com
Background Antibiotics can disturb gastrointestinal microbiota which may lead to reduced
resistance to pathogens such as Clostridium difficile (C. difficile). Probiotics are live …

Probiotics for the Primary and Secondary Prevention of C. difficile Infections: A Meta-analysis and Systematic Review

LV McFarland - Antibiotics, 2015 - mdpi.com
Clostridium difficile infections are a global clinical concern and are one of the leading
causes of nosocomial outbreaks. Preventing these infections has benefited from …

The mechanisms and efficacy of probiotics in the prevention of Clostridium difficile-associated diarrhoea

GC Parkes, JD Sanderson, K Whelan - The Lancet infectious …, 2009 - thelancet.com
The proportion and severity of Clostridium difficile-associated diarrhoea (CDAD) is
increasing in health-care settings. Antibiotics remain the most important risk factor for CDAD …

Prevention of Clostridium difficile Infection With Probiotics

CT Evans, S Johnson - Clinical Infectious Diseases, 2015 - academic.oup.com
Despite advances in the diagnosis and treatment of Clostridium difficile infection (CDI) and
prevention efforts to reduce the spread of C. difficile, CDI remains a significant challenge to …