Cyclin-dependent kinases as a therapeutic target for stroke
…, S Osuga, F Wang, R Fetni, MJ Hogan… - Proceedings of the …, 2000 - National Acad Sciences
Cyclin-dependent kinases (CDKs) are commonly known to regulate cell proliferation.
However, previous reports suggest that in cultured postmitotic neurons, activation of CDKs is a …
However, previous reports suggest that in cultured postmitotic neurons, activation of CDKs is a …
Effects of prenatal marijuana on response inhibition: an fMRI study of young adults
The neurophysiological effects of prenatal marijuana exposure on response inhibition were
assessed in 18- to 22-year-olds. Thirty-one participants from the Ottawa Prenatal …
assessed in 18- to 22-year-olds. Thirty-one participants from the Ottawa Prenatal …
Effects of prenatal marijuana on visuospatial working memory: an fMRI study in young adults
The long lasting neurophysiological effects of prenatal marijuana exposure on visuospatial
working memory were investigated in 18–22 year olds using functional magnetic resonance …
working memory were investigated in 18–22 year olds using functional magnetic resonance …
Cortical spreading depression protects against subsequent focal cerebral ischemia in rats
K Matsushima, MJ Hogan… - Journal of Cerebral Blood …, 1996 - journals.sagepub.com
The possibility that cortical spreading depression (CSD) may have neuroprotective action
during subsequent focal cerebral ischemia was examined in rats. Three days before the …
during subsequent focal cerebral ischemia was examined in rats. Three days before the …
Effects of marijuana on visuospatial working memory: an fMRI study in young adults
AM Smith, CA Longo, PA Fried, MJ Hogan… - …, 2010 - Springer
Objectives The effects of marijuana use on visuospatial working memory were investigated
in 19–21-year-olds using functional magnetic resonance imaging (fMRI). Methods …
in 19–21-year-olds using functional magnetic resonance imaging (fMRI). Methods …
White Matter Thresholds for Ischemic Penumbra and Infarct Core in Patients with Acute Stroke: CT Perfusion Study1
…, AJ Fox, DH Lee, DJ Sahlas, SE Black, MJ Hogan… - Radiology, 2008 - pubs.rsna.org
Purpose: To prospectively determine the parameters derived at admission computed
tomographic (CT) perfusion imaging admission that best differentiate ischemic white matter that …
tomographic (CT) perfusion imaging admission that best differentiate ischemic white matter that …
Calcium‐mediated mechanisms of ischemic injury and protection
P Morley, MJ Hogan, AM Hakim - Brain Pathology, 1994 - Wiley Online Library
Our understanding of calcium's role in cerebral ischemia continues to evolve from the initial
recognition that it may be harmful to the ischemic cell. A multitude of experiments have …
recognition that it may be harmful to the ischemic cell. A multitude of experiments have …
Cortical spreading depression activates trophic factor expression in neurons and astrocytes and protects against subsequent focal brain ischemia
K Matsushima, R Schmidt-Kastner, MJ Hogan… - Brain research, 1998 - Elsevier
We recently reported that cortical spreading depression (CSD), used to precondition rat
brain, reduced cortical infarction volume resulting from focal cerebral ischemia by middle …
brain, reduced cortical infarction volume resulting from focal cerebral ischemia by middle …
Preconditioning with cortical spreading depression decreases intraischemic cerebral glutamate levels and down‐regulates excitatory amino acid transporters EAAT1 …
AG Douen, K Akiyama, MJ Hogan… - Journal of …, 2000 - Wiley Online Library
We previously reported a 50% reduction in cortical infarct volume following transient focal
cerebral ischemia in rats preconditioned 3 days earlier with cortical spreading depression (…
cerebral ischemia in rats preconditioned 3 days earlier with cortical spreading depression (…
Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat
…, JE Ikeda, RS Slack, MJ Hogan… - Journal of Cerebral …, 2002 - journals.sagepub.com
Increasing evidence suggests that cyclin-dependent kinases participate in neuronal death
induced by multiple stresses in vitro. However, their role in cell death paradigms in vivo is not …
induced by multiple stresses in vitro. However, their role in cell death paradigms in vivo is not …