Identification of a transcriptional signature for the wound healing continuum

MA Peake, M Caley, PJ Giles, I Wall… - Wound Repair and …, 2014 - Wiley Online Library
There is a spectrum/continuum of adult human wound healing outcomes ranging from the
enhanced (nearly scarless) healing observed in oral mucosa to scarring within skin and the …

[HTML][HTML] Role of enzymic antioxidants in mediating oxidative stress and contrasting wound healing capabilities in oral mucosal/skin fibroblasts and tissues

…, F Ruge, JN Farrier, S Enoch, MP Caley, MA Peake… - Antioxidants, 2023 - mdpi.com
Unlike skin, oral mucosal wounds are characterized by rapid healing and minimal scarring,
attributable to the “enhanced” healing properties of oral mucosal fibroblasts (OMFs). As …

'Young'oral fibroblasts are geno/phenotypically distinct

S Enoch, MA Peake, I Wall, L Davies… - Journal of dental …, 2010 - journals.sagepub.com
Wound healing within the oral mucosa results in minimal scar formation compared with wounds
within the skin. We have recently demonstrated distinct differences in the aging profiles …

Alternatives for animal wound model systems

P Stephens, M Caley, M Peake - Wound Regeneration and Repair …, 2013 - Springer
In this chapter a review of animal model systems already being utilized to study normal and
pathologic wound healing is provided. We also go into details on alternatives for animal …

[HTML][HTML] Preliminary characterisation of mechanoresponsive regions of the c-fos promoter in bone cells

MA Peake, AJ El Haj - FEBS letters, 2003 - Elsevier
Preliminary analysis of the mechanisms involved in induction of stretch-mediated
transcriptional activity in the c-fos promoter of bone has been undertaken using a series of c-fos …

[HTML][HTML] Development and characterisation of a human chronic skin wound cell line—towards an alternative for animal experimentation

M Caley, IB Wall, M Peake, D Kipling, P Giles… - International journal of …, 2018 - mdpi.com
Background: Chronic skin wounds are a growing financial burden for healthcare providers,
causing discomfort/immobility to patients. Whilst animal chronic wound models have been …

Poem: Untitled

M Peake - CMAJ: Canadian Medical Association Journal, 2006 - ncbi.nlm.nih.gov
I've spent time screaming, cursing, pleading, threatening the moon because I thought it was
God's eye and wanted his attention it never blinked but I still didn't get a response Earth's …

A LIFETIME OF HOOP-JUMPING; FIRST PERSON

M Peake - Globe & Mail (Toronto, Canada), 2020 - go.gale.com
I bought my first car in 2001, when I was 24 years old. At that point, I'd put together a rather
impressive driving resume consisting of four accidents, three flat tires and multiple tow-truck …

MANAGING THE RISK OF TRANSFORMER BUSHING FAILURE-Project Assessment Conclusions Report Summary

MEN Peake - 2018 - policycommons.net
2 Managing the Risk of Transformer Bushing Failure Project Assessment Conclusions Report
Executive Summary This report is the final stage of an investigation of the most economic …

Identifying a Gene signature for the wound healing continuum

MA Peake, PJ Giles, IB Wall, S Enoch… - Wound Repair and …, 2008 - orca.cardiff.ac.uk
Introduction: There is a deleterious effect upon wound healing functionality associated with
increasing age with a continuum between old and young. Oral mucosal fibroblasts (OMFs) …