Background There have been few detailed, in-person interviews and examinations to obtain
follow-up data on 5-year outcomes among survivors of the acute respiratory distress …

Background As more patients survive the acute respiratory distress syndrome, an understanding
of the long-term outcomes of this condition is needed. Methods We evaluated 109 …

We have developed a simple and reproducible rat model of chronic colonic inflammation by
the intraluminal instillation of a solution containing a “barrier breaker” and a. hapten. …

Objective: Survivors of severe critical illness frequently develop substantial and persistent
physical complications, including muscle weakness, impaired physical function, and …

Objective: To determine how the quality of life (QOL) of intensive care unit (ICU) survivors
compares with the general population, changes over time, and is predicted by baseline …

Acute lung injury (ALI) and its presentation with more severe hypoxemia, the ARDS, is a
challenging entity for clinical investigation because, like many critical illness syndromes, it lacks …

Background: Surveys have documented the continued popularity of low-dose dopamine to
influence renal dysfunction even though few data support it and editorials and reviews have …

Outcomes after Critical Illness Critical illness is a transformative and often traumatic event for
the entire family. The authors summarize data on the outcomes and highlight the need to …

Rationale: Diaphragm dysfunction worsens outcomes in mechanically ventilated patients,
but the clinical impact of potentially preventable changes in diaphragm structure and function …

Rationale: Diaphragm atrophy and dysfunction have been reported in humans during
mechanical ventilation, but the prevalence, causes, and functional impact of changes in …