Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer

…, JS Ginsberg, C Kearon, M Gent… - Thrombosis and …, 2000 - thieme-connect.com
We have previously demonstrated that a clinical model can be safely used in a management
strategy in patients with suspected pulmonary embolism (PE). We sought to simplify the …

Platelet-active drugs: the relationships among dose, effectiveness, and side effects

…, B Coller, JE Dalen, GAF Gerald, V Fuster, M Gent… - Chest, 2001 - journal.chestnet.org
Abbreviations: ACE trial Acetylsalicylic Acid and Carotid Endarterectomy; ADP adenosine
diphosphate; AMP adenosine monophosphate; CAPRIE study Clopidogrel vs Aspirin in …

The Canadian American ticlopidine study (CATS) in thromboembolic stroke

M Gent, JD Easton, VC Hachinski, E Panak, J Sicurella… - The Lancet, 1989 - Elsevier
Gent M, Sackett DL. The qualification and disqualification of patients and events in long-term …
Sackett DL, Gent M. Controversy in counting and attributing events in clinical trials N Engl J …

Canadian Implantable Defibrillator Study (CIDS) a randomized trial of the implantable cardioverter defibrillator against amiodarone

SJ Connolly, M Gent, RS Roberts, P Dorian, D Roy… - Circulation, 2000 - Am Heart Assoc
Background—Patients surviving ventricular fibrillation (VF) or sustained ventricular
tachycardia (VT) are at a high risk of death due to a recurrence of arrhythmia. The implantable …

A comparison of low-molecular-weight heparin administered primarily at home with unfractionated heparin administered in the hospital for proximal deep-vein …

M Levine, M Gent, J Hirsh, J Leclerc… - … England Journal of …, 1996 - Mass Medical Soc
Background Patients with acute proximal deep-vein thrombosis are usually treated first in
the hospital with intravenous standard (unfractionated) heparin. However, the longer plasma …

Platelet-active drugs: the relationships among dose, effectiveness, and side effects

C Patrono, B Coller, JE Dalen, V Fuster, M Gent… - Chest, 1998 - journal.chestnet.org
S ince our last report on antithrornbotic therapy in 1995, 1 new information has been published
on the role of aspirin and other platelet-active drugs in the treatment and prevention of …

A comparison of three months of anticoagulation with extended anticoagulation for a first episode of idiopathic venous thromboembolism

C Kearon, M Gent, J Hirsh, J Weitz… - … England Journal of …, 1999 - Mass Medical Soc
Background Patients who have a first episode of venous thromboembolism in the absence
of known risk factors for thrombosis (idiopathic thrombosis) are often treated with …

Aspirin, sulfinpyrazone, or both in unstable angina: results of a Canadian multicenter trial

JA Cairns, M Gent, J Singer, KJ Finnie… - … England Journal of …, 1985 - Mass Medical Soc
We performed a randomized, double-blind, placebo-controlled trial in 555 patients with
unstable angina who were hospitalized in coronary care units. Patients received one of four …

Intra-arterial prourokinase for acute ischemic stroke: the PROACT II study: a randomized controlled trial

…, L Wechsler, M Gent, H Rowley, C Kase, M Pessin… - Jama, 1999 - jamanetwork.com
… both the M 1 and M 2 segments of the middle cerebral artery. … 1) of either the M 1 segment
or an M 2 division of the MCA. … of an artery other than the M 1 or M 2 MCA. All patients with …

[HTML][HTML] Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer

…, JA Julian, S Haley, MJ Kovacs, M Gent - New England journal …, 2003 - Mass Medical Soc
Background Patients with cancer have a substantial risk of recurrent thrombosis despite the
use of oral anticoagulant therapy. We compared the efficacy of a low-molecular-weight …