Brain enlargement has been observed in children with autism spectrum disorder (ASD), but
the timing of this phenomenon, and the relationship between ASD and the appearance of …

Early identification of autism spectrum disorder (ASD) is essential to ensure that children
can access specialized evidence-based interventions that can help to optimize long-term …

The Autism Observation Scale for Infants (AOSI) was developed to detect and monitor early
signs of autism as they emerge in high-risk infants (all with an older sibling with an autistic …

In the interest of more systematically documenting the early signs of autism, and of testing
specific hypotheses regarding their underlying neurodevelopmental substrates, we have …

Structural variation (copy number variation [CNV] including deletion and duplication,
translocation, inversion) of chromosomes has been identified in some individuals with autism …

OBJECTIVE: The recurrence risk of autism spectrum disorders (ASD) is estimated to be
between 3% and 10%, but previous research was limited by small sample sizes and biases …

Rare copy-number variation (CNV) is an important source of risk for autism spectrum
disorders (ASDs). We analyzed 2,446 ASD-affected families and confirmed an excess of genic …

This article reviews current evidence for autism spectrum disorder (ASD) interventions for
children aged <3 years, based on peer-reviewed articles published up to December 2013. …

Objective: Evidence from prospective studies of high-risk infants suggests that early symptoms
of autism usually emerge late in the first or early in the second year of life after a period of …

Mutations in SHANK3, which encodes a synaptic scaffolding protein, have been described in
subjects with an autism spectrum disorder (ASD). To assess the quantitative contribution of …