Inflammasomes are large cytoplasmic complexes that sense microbial infections/danger
molecules and induce caspase-1 activation-dependent cytokine production and macrophage …

Multicellular organisms initiate adaptive responses when oxygen (O 2 ) availability decreases,
but the underlying mechanism of O 2 sensing remains elusive. We find that functionality of …

Photodynamic therapy (PDT) has been extensively investigated for decades for tumor
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …

Microglia are myeloid cells of the CNS that participate both in normal CNS function and in
disease. We investigated the molecular signature of microglia and identified 239 genes and 8 …

Background The role of endovascular therapy for acute stroke with a large infarction has not
been extensively studied in differing populations. Methods We conducted a multicenter, …

Background Stroke is common during the first few weeks after a transient ischemic attack (TIA)
or minor ischemic stroke. Combination therapy with clopidogrel and aspirin may provide …

At the same time as the world recognizes the rapid economic development in China, Chinese
healthcare system has also had significant improvement. However, this nation of 1.4 billion …

Aim Stroke is the leading cause of disability and death in China. Ischaemic stroke accounts
for about 60%–80% of all strokes. It is of considerable significance to carry out …

Oxygen (O 2 ) deprivation, or hypoxia, has profound effects on cell metabolism and growth.
Cells can adapt to low O 2 in part through activation of hypoxia-inducible factor (HIF). We …

The technology acceptance model proposes that perceived ease of use and perceived
usefulness predict the acceptance of information technology. Since its inception, the model has …