2. Broersen LHA, Pereira AM, Jørgensen JOL, et al. Adrenal insufficiency in corticosteroids
use: systematic review and meta-analysis. J Clin Endo crinol Metab 2015; 100: 2171-80. 3 …

In their recent review of intranasal corticosteroids, the authors claim that there is no
correlation with hypothalamic-pituitary-adrenal suppression (1). However, there are …

In their recent CMAJ Practice article on intranasal corticosteroids, Drs. Fowler and Sowerby1
stated that this therapy is not associated with hypothalamic–pituitary–adrenal (HPA) axis …

Thank you to Dr. Kline and his co-authors for their insightful comments regarding the
potential risk of HPA axis suppression in certain scenarios with nasal corticosteroid (1). We …

3. Orlandi RR, Kingdom TT, Hwang PH, et al. International consensus statement on allergy
and rhinology: rhinosinusitis. Int Forum Allergy Rhinol 2016; 6: S22209. 4. Gupta R …

Background Intranasal corticosteroids (INCS) are used in the management of sinonasal
conditions. Use of exogenous steroids can be associated with hypothalamic‐pituitary …

Objectives To address concerns related to the safety profile of both Food and Drug
Administration (FDA)–approved and non–FDA-approved intranasal corticosteroid (INCS) …

The Joint Task Force for the American Academy of Allergy, Asthma and Immunology and the
American College of Allergy, Asthma and Immunology was charged with formulating a …

Background In the specialty of Otolaryngology–Head and Neck Surgery, intranasal
corticosteroids are the mainstay treatment for inflammatory processes within the nasal cavity …

It has been almost 50 years since Niels Mygind published the first paper on the use of nasal
corticosteroids. Twenty years ago, Weiner et al. showed in their systematic review that nasal …