TRAIL (also called Apo2L) belongs to the tumor necrosis factor family, activates rapid
apoptosis in tumor cells, and binds to the death-signaling receptor DR4. Two additional TRAIL …

Increased levels of B lymphocyte stimulator (BLyS) are associated with systemic
autoimmunity in animal models of spontaneous autoimmune disease, and transgenic animals …

Objective To identify and characterize a fully human antibody directed against B lymphocyte
stimulator (BLyS), a tumor necrosis factor–related cytokine that plays a critical role in the …

Objective To assess the overexpression of B lymphocyte stimulator (BLyS) over time in
patients with systemic lupus erythematosus (SLE). Methods Sixty‐eight SLE patients were …

A large-scale effort, termed the Secreted Protein Discovery Initiative (SPDI), was undertaken
to identify novel secreted and transmembrane proteins. In the first of several approaches, a …

Exposures to uncontrollable stress have been shown to alter ensuing synaptic plasticity in
the hippocampus and interfere with hippocampal-dependent spatial memory in rats. The …

BLyS and APRIL are two members of the TNF superfamily that are secreted by activated
myeloid cells and have costimulatory activity on B cells. BLyS and APRIL share two receptors, …

An expression cloning approach was employed to identify the receptor for B-lymphocyte
stimulator (BLyS) and identified the tumor necrosis factor receptor superfamily member TACI as …

The IL-1 family of cytokines currently comprises of seven ligands with pro-inflammatory
activity (IL-1α and IL-1β, IL-18, IL-33, IL-36α, IL-36β, IL-36γ) as well as two ligands with anti-…

Orbital debris in low Earth orbit (LEO) are now sufficiently dense that the use of LEO space is
threatened by runaway collision cascading. A problem predicted more than thirty years ago…