Background: Vitamin D sufficiency is associated with better inflammatory outcomes in
multiple sclerosis (MS). We hypothesize that it is also associated with better long-term …

Objective: The primary objective of this study was to explore the potential influence of gender
on recovery from optic neuritis (ON) by determining whether differences in retinal nerve …

There is accumulating evidence of sex differences in multiple sclerosis, making hormones a
possible research avenue for therapeutic agents. Oral contraceptives are a source of …

Objective: To longitudinally compare the male and female retinal nerve fiber layer (RNFL)
values in an multiple sclerosis (MS) cohort. Background Multiple sclerosis is a demyelinating …

Background: The chronic cerebrospinal venous insufficiency theory proposes that altered
cerebral venous hemodynamics play a role in the pathophysiology of multiple sclerosis. We …

OBJECTIVE: We hypothesize that vitamin D sufficiency (25(OH)D > 80 nmol/L) is associated
with better optical coherence tomography (OCT) outcomes and axonal preservation/…

OBJECTIVE: To document incidental findings detected by MRI/MR venography of the head
and neck in an ongoing observational study designed to detect features of chronic …

Purpose To test the feasibility of using multi-scale MRI texture analysis to assess optic nerve
pathology and to investigate how visual recovery relates to the severity of acute tissue …

Purpose: Diffusion tensor imaging (DTI) has demonstrated optic nerve damage associated
with optic neuritis (ON); however, the usefulness of mean fractional anisotropy (FA) …

Objective: Given that estrogen has been postulated to have a neuro-protective effect at the
optic nerve head, we hypothesized that men would have lower retinal nerve fiber layer (RNFL…