Point-of-care β-lactam allergy skin testing by antimicrobial stewardship programs: a pragmatic multicenter prospective evaluation

…, JB McCready, P Das, B Minnema… - Clinical Infectious …, 2017 - academic.oup.com
Background β-lactam allergy skin testing (BLAST) is recommended by antimicrobial
stewardship program (ASP) guidelines, yet few studies have systematically evaluated its impact …

[HTML][HTML] Necrotic pulmonary nodules in secondary syphilis

JB McCready, R Skrastins, JF Downey, JE Powis - CMAJ, 2011 - Can Med Assoc
Discussion The rate of primary and secondary syphilis in Canada increased by 500% between
1998 and 2007, from 177 cases reported in 1999 to 1206 in 2007. 1 Similar increases …

Optimizing preoperative prophylaxis in patients with reported β-lactam allergy: a novel extension of antimicrobial stewardship

A Vaisman, J McCready, S Hicks… - Journal of Antimicrobial …, 2017 - academic.oup.com
Background Use of alternative second-line antibiotics is associated with adverse events in
patients reporting β-lactam allergy. In the perioperative setting, we hypothesized that …

[HTML][HTML] Peginterferon lambda for the treatment of outpatients with COVID-19: a phase 2, placebo-controlled randomised trial

…, J McCready, DHS Tan, T Chan, B Coburn… - The Lancet …, 2021 - thelancet.com
Background To date, only monoclonal antibodies have been shown to be effective for
outpatients with COVID-19. Interferon lambda-1 is a type III interferon involved in innate antiviral …

[HTML][HTML] Detection of SARS-CoV-2 from saliva as compared to nasopharyngeal swabs in outpatients

C Kandel, J Zheng, J McCready, MA Serbanescu… - Viruses, 2020 - mdpi.com
Widely available and easily accessible testing for COVID-19 is a cornerstone of pandemic
containment strategies. Nasopharyngeal swabs (NPS) are the currently accepted standard for …

Assessment of a 2-step urine culture ordering process for detecting asymptomatic bacteruria among hospitalized patients

MT Taylor, J McCready, T Havey, S Kaur… - JAMA Network …, 2020 - jamanetwork.com
Educational interventions attempting to reduce the treatment of asymptomatic bacteruria
and candiduria (ASB/C) have been largely unsuccessful. Modifying how urine cultures (UCs) …

Impact of two-step urine culture ordering in the emergency department: a time series analysis

…, A Kaufman, J Leis, J McCready… - BMJ quality & …, 2018 - qualitysafety.bmj.com
Background Despite evidence against the use of antimicrobials for asymptomatic bacteriuria
(ASB), they are frequently prescribed leading to unnecessary adverse events. Prior studies …

[HTML][HTML] Every antibiotic, every day: maximizing the impact of prospective audit and feedback on total antibiotic use

TJ Campbell, M Decloe, S Gill, G Ho, J McCready… - PLoS …, 2017 - journals.plos.org
Background The success of antimicrobial stewardship is dependent on how often it is
completed and which antimicrobials are targeted. We evaluated the impact of an antimicrobial …

Impact of a multifaceted antimicrobial stewardship program: a front-line ownership driven quality improvement project in a large urban emergency department

AJ Kaufman, J McCready, J Powis - Canadian Journal of Emergency …, 2017 - cambridge.org
BackgroundAntibiotic overuse has promoted growing rates of antimicrobial resistance and
secondary antibiotic-associated infections such as Clostridium difficile (C. difficile). …

Viral dynamics of the SARS-CoV-2 Omicron Variant among household contacts with 2 or 3 COVID-19 vaccine doses

C Kandel, Y Lee, M Taylor, A Llanes, J McCready… - Journal of Infection, 2022 - Elsevier
Objectives SARS-CoV-2 shedding has changed as new variants have emerged. It is important
to understand the trajectory of PCR positivity due to Omicron in vaccinated populations. …