Sex-hormone-driven innate antibodies protect females and infants against EPEC infection

…, R Devinney, GC Thompson, J Blackwood… - Nature …, 2018 - nature.com
Females have an overall advantage over males in resisting Gram-negative bacteremias,
thus hinting at sexual dimorphism of immunity during infections. Here, through intravital …

Does teaching crisis resource management skills improve resuscitation performance in pediatric residents?

J Blackwood, JP Duff, A Nettel-Aguirre… - Pediatric Critical Care …, 2014 - journals.lww.com
Objective: The effect of teaching crisis resource management skills on the resuscitation
performance of pediatric residents is unknown. The primary objective of this pilot study was to …

[HTML][HTML] Development of metabolic and inflammatory mediator biomarker phenotyping for early diagnosis and triage of pediatric sepsis

B Mickiewicz, GC Thompson, J Blackwood, CN Jenne… - Critical care, 2015 - Springer
Introduction The first steps in goal-directed therapy for sepsis are early diagnosis followed
by appropriate triage. These steps are usually left to the physician’s judgment, as there is no …

Association of hemoglobin and transfusion with outcome after operations for hypoplastic left heart

J Blackwood, AR Joffe, CMT Robertson, IA Dinu… - The Annals of thoracic …, 2010 - Elsevier
BACKGROUND: Red blood cell transfusions may or may not improve oxygen delivery to the
tissues. Some studies suggest transfusion might contribute to adverse outcomes. This study …

Evaluating the introduction of extracorporeal life support technology to a tertiary-care pediatric institution: smoothing the learning curve through interprofessional …

…, ME Brindle, T Spence, J Blackwood… - Journal of Pediatric …, 2015 - Elsevier
Background Extracorporeal life support (ECLS) is a life-saving technology for the critically ill
child. Our objective was to evaluate the outcomes of an educational curriculum designed to …

Setting up a rescue extracorporeal life support program

J Blackwood, D Nikitovic, T Spence, GK Khaira… - ASAIO …, 2022 - journals.lww.com
Extracorporeal life support (ECLS) is a high-risk, lifesaving medical treatment that is typically
limited to centers that can support a comprehensive ECLS program. Rescue programs can …

Key considerations in establishing a pediatric rescue extracorporeal life support program: A multi methods review

J Blackwood, A Zadunayski, T Spence, D Nikitovic… - ASAIO …, 2022 - journals.lww.com
Extracorporeal life support (ECLS) is generally limited to centers with cardiac surgery.
However, pediatric centers without cardiac surgery can still provide potentially lifesaving ECLS …

Cytokines and chemokines in pediatric appendicitis: a multiplex analysis of inflammatory protein mediators

…, GC Thompson, AR Joffe, J Blackwood… - Mediators of …, 2019 - Wiley Online Library
Objectives. We aimed to demonstrate the potential of precision medicine to describe the
inflammatory landscape present in children with suspected appendicitis. Our primary objective …

[HTML][HTML] Metabolomic and inflammatory mediator based biomarker profiling as a potential novel method to aid pediatric appendicitis identification

NS Shommu, CN Jenne, J Blackwood, AR Joffe… - PLoS …, 2018 - journals.plos.org
Various limitations hinder the timely and accurate diagnosis of appendicitis in pediatric
patients. The present study aims to investigate the potential of metabolomics and cytokine …

[HTML][HTML] Optimizing provision of extracorporeal life support during the COVID-19 pandemic: practical considerations for Canadian jurisdictions

KKS Parhar, L Lequier, J Blackwood, DJ Zuege… - CMAJ, 2020 - Can Med Assoc
During pandemics, surges in patients requiring critical care resources are anticipated and
can swiftly overwhelm a health care system. 10 Public health efforts to slow person-to-person …