Drug interactions occur when the efficacy or toxicity of a medication is changed by administration
of another substance. Pharmacokinetic interactions often occur as a result of a change …

Objective: To assess the efficacy of carotid endarterectomy for stroke prevention in
asymptomatic and symptomatic patients with internal carotid artery stenosis. Additional clinical …

Elevated plasma homocysteine levels have been associated with higher risks of cardiovascular
disease, but the effects on disease rates of supplementation with folic acid to lower …

Jonathan D. Spence is George Burton Adams Professor of History at Yale University and
author of eight acclaimed books on China. Here he has written a very readable history of this …

Background Previous studies have shown that carotid endarterectomy in patients with
symptomatic severe carotid stenosis (defined as stenosis of 70 to 99 percent of the luminal …

ContextIn observational studies, elevated plasma total homocysteine levels have been
positively associated with ischemic stroke risk. However the utility of homocysteine-lowering …

Background Atrial fibrillation is a leading preventable cause of recurrent stroke for which
early detection and treatment are critical. However, paroxysmal atrial fibrillation is often …

… Spence has written many other books on Chinese history, including Treason By the Book,
Mao Zedong, God's Chinese Son: The Taiping Heavenly Kingdom of Hong Xiuquan, To …

Background Patients with ischemic stroke or transient ischemic attack (TIA) are at increased
risk for future cardiovascular events despite current preventive therapies. The identification …

Background The efficacy of closure of a patent foramen ovale (PFO) in the prevention of
recurrent stroke after cryptogenic stroke is uncertain. We investigated the effect of PFO closure …