Narrative review: the role of leptin in human physiology: emerging clinical applications

T Kelesidis, I Kelesidis, S Chou… - Annals of internal …, 2010 - acpjournals.org
Leptin is a hormone secreted by adipose tissue in direct proportion to amount of body fat. The
circulating leptin levels serve as a gauge of energy stores, thereby directing the regulation …

Detection of left atrial appendage thrombus by cardiac computed tomography in patients with atrial fibrillation: a meta-analysis

J Romero, SA Husain, I Kelesidis, J Sanz… - Circulation …, 2013 - Am Heart Assoc
Background— Transesophageal echocardiogram (TEE) is considered the gold standard
modality in detecting left atrial/LA appendage (LA/LAA) thrombi. However, this is a semi-…

Counterfeit or substandard antimicrobial drugs: a review of the scientific evidence

T Kelesidis, I Kelesidis, PI Rafailidis… - Journal of …, 2007 - academic.oup.com
There is growing universal concern regarding counterfeit medications. In particular, counterfeit
antimicrobial drugs are a threat to public health with many devastating consequences for …

Total and High-Molecular-Weight Adiponectin in Breast Cancer: In Vitro and in Vivo Studies

…, T Kelesidis, I Kelesidis… - The Journal of …, 2007 - academic.oup.com
Background: Obesity is a major risk factor for breast cancer. We hypothesized that obesity-induced
decreases in total and/or high-molecular-weight (HMW) adiponectin levels may …

Tigecycline for the treatment of multidrug-resistant (including carbapenem-resistant) Acinetobacter infections: a review of the scientific evidence

…, T Kelesidis, I Kelesidis… - Journal of …, 2008 - academic.oup.com
Objectives New antibacterial agents are required for the treatment of infections caused by
multidrug-resistant (MDR) Acinetobacter spp. Whether tigecycline constitutes an effective …

Human infections associated with wild birds

S Tsiodras, T Kelesidis, I Kelesidis, U Bauchinger… - Journal of Infection, 2008 - Elsevier
INTRODUCTION: Wild birds and especially migratory species can become long-distance
vectors for a wide range of microorganisms. The objective of the current paper is to summarize …

Tigecycline for the treatment of multidrug-resistant Enterobacteriaceae: a systematic review of the evidence from microbiological and clinical studies

T Kelesidis, DE Karageorgopoulos… - Journal of …, 2008 - academic.oup.com
Objectives Antimicrobial drug resistance is spreading among Enterobacteriaceae, limiting
the utility of traditionally used agents. We sought to systematically review the microbiological …

Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans

…, GK Shetty, P Raciti, I Kelesidis… - Proceedings of the …, 2006 - National Acad Sciences
To elucidate whether the role of leptin in regulating neuroendocrine and immune function
during short-term starvation in healthy humans is permissive, ie, occurs only when circulating …

Coronary computed tomography angiography for the detection of cardiac allograft vasculopathy: a meta-analysis of prospective trials

O Wever-Pinzon, J Romero, I Kelesidis… - Journal of the American …, 2014 - jacc.org
Objectives : This study aimed to evaluate the diagnostic accuracy of coronary computed
tomography angiography (CCTA) for detecting cardiac allograft vasculopathy (CAV) in …

Leptin does not mediate short-term fasting-induced changes in growth hormone pulsatility but increases IGF-I in leptin deficiency states

…, J Blakeman, T Kelesidis, I Kelesidis… - The Journal of …, 2008 - academic.oup.com
Context: States of acute and chronic energy deficit are characterized by increased GH
secretion and decreased IGF-I levels. Objective: The objective of the study was to determine …