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This practice point provides a framework for initiating investigation in children suspected of
having infection with Mycobacterium tuberculosis (Mtb). Some areas in Canada have a high …

TERMINOLOGY A positive Mantoux tuberculin skin test is the hallmark of tuberculous
infection, meaning that the person harbors M tuberculosis within the body. If the individual …

Although often regarded as a foreign disease, latent tuberculosis or tuberculosis disease will
be encountered in many clinical situations by the Canadian child health practitioner. There …

Although childhood tuberculosis has declined dramatically in the UK over the last century, it
is now increasing again and globally childhood tuberculosis still accounts for a significant …

Childhood tuberculosis accounts for a significant proportion of the global tuberculosis
disease burden. However, tuberculosis in children is difficult to diagnose, because disease …

Tuberculosis (TB) remains an important problem among children in the United States and
throughout the world. There is no diagnostic reference standard for latent tuberculosis …

These new guidelines have significant implications for improving pediatric TB care.
Regarding diagnosis, current interferon-gamma release assays should not replace …

Childhood tuberculosis poses great challenges to the public health mangers as well as the
pediatrician. While mycobacterial detection and isolation remain the gold standard but has a …

About one million children develop tuberculosis (TB) annually worldwide, accounting for
about 11% of all TB cases. Children with TB differ from adults in their immunological and …