In recent years, doubt has been shed on the necessity of mastectomy for women with early-stage
breast cancer. Apart from purely medical studies comparing (radical) mastectomy to …

In 1985, the EORTC Radiotherapy Co-operative Group launched a randomised phase III
study comparing high-dose (59.4Gy in 6.5 weeks) versus low-dose (45Gy in 5 weeks) …

OBJECTIVE: To assess whether patient preferences regarding information and participation
in decision-making about treatment options are related to patient characteristics and the …

Background Operative procedures for primary rectal cancer from Japan combine pelvic
nerve-preserving techniques with radical tumour resection to ensure optimal local tumour control …

The standard gamble (SG) and the time tradeoff (TTO), two frequently used methods of utility
assessment, have often been found to lead to different utilities for the same health state. …

The patient's perspective is of prime concern in weighing the benefits and side effects of
oncologic treatment. Little is known about patients' preferences and attitudes. The authors …

Methods often used for the valuation of health states are the time trade-off (TTO) and the
visual analog scale (VAS). The VAS is easier than the TTO and can be self-administered; …

… GM Kiebert and J. Kievit are at Medical Decision Making/Department of Surgery; JHCJM
de Haes is at Medical Decision Making/Department of … GM Kiebert et al. … GM Kiebert et al. …

Objectives: Amyotrophic lateral sclerosis (ALS) is a devastating disease that has serious
consequences in terms of impairments and disabilities, which are expected to impact on health-…

We examined the feasibility and the proportional trade-off assumption of the Time Trade-Off
method. Utilities were assessed of the actual health states of 54 testicular and 72 colorectal …