Easing the disruption of COVID-19: supporting the mental health of the people of Canada—October 2020—an RSC policy briefing

…, C Blackstock, MC Bourque, G Brimacombe… - Facets, 2020 - facetsjournal.com
The COVID-19 pandemic has had a significant impact on the mental health of the people of
Canada. Most have found it challenging to cope with social distancing, isolation, anxiety …

Design of continuous casting machines based on a heat-flow analysis: state-of-the-art review

JK Brimacombe - Canadian Metallurgical Quarterly, 1976 - Taylor & Francis
… by Savage and Pritchard<G>, that can be used to describe mathematically … section of a
10- by 15-cm billet after 118G surface reheat below the sprays (from Grill, Brimacombe and …

Core and comprehensive health care services: 4. Economic issues.

M Wyman, J Feeley, G Brimacombe… - CMAJ: Canadian …, 1995 - ncbi.nlm.nih.gov
This article reviews the economic dimensions of the CMA's decision-making framework on
core and comprehensive services. The framework was developed in a policy context …

[PDF][PDF] Health, healthcare and nation-building: A three dimensional approach to innovation in Canada

GG Brimacombe - Healthcare Quarterly, 2005 - ualberta.ca
Since the early to mid-1990s, Canadians have witnessed and participated in an emotion-laden
debate about the future of health and healthcare. While the issues of timely access to a …

Securing the future of Canada's Academic Health Sciences Centres.

G Brimacombe - Healthcare quarterly (Toronto, Ont.), 2004 - europepmc.org
Although there have been a number of in-depth national, federal, provincial and territorial
reviews of the health system in Canada, there has not been a systematic review of the current …

LMA ProSealTM vs. i‐GelTM in ventilated children: A randomised, crossover study using the size 2 mask

L Gasteiger, J Brimacombe, E Oswald… - Acta …, 2012 - Wiley Online Library
Background The L aryngeal M ask A irway ( LMA ) ProSeal TM and the i‐ G el TM are two
extraglottic devices with either an inflatable cuff or a non‐inflatable cuff. Aim We test the …

Ribosome structure

R Brimacombe, G Stoffler… - Annual review of …, 1978 - annualreviews.org
218 BRIMACOMBE, STOFFLER & WITTMANN in a number of steps that can be studied in
vitro. In order to perform such an intricate function, the ribosome itself is necessarily a complex …

… conserved GTPase-associated center of the ribosome induced by mutagenesis influences the structure of peptidyltransferase center and activity of elongation factor G

…, AA Leonov, AA Bogdanov, R Brimacombe… - Journal of Biological …, 2005 - ASBMB
Translocation catalyzed by elongation factor G occurs after the peptidyltransferase … -G. We
suggest that the allosteric signal from the peptidyltransferase center that activates EF-G may …

Where the O2 goes to: preservation of human fetal oxygen delivery and consumption at high altitude

…, W Tellez, I Maldonado, M Brimacombe… - The Journal of …, 2009 - Wiley Online Library
… Altitude-associated decrease in birth weight was greater in Europeans (−417 g) than Andeans
(−228 g, P < 0.005). Birth weight at 3600 m was > 200 g lower for Europeans at any given …

Pyrazole-based lactate dehydrogenase inhibitors with optimized cell activity and pharmacokinetic properties

…, GL Squadrito, KR Brimacombe… - Journal of medicinal …, 2020 - ACS Publications
Lactate dehydrogenase (LDH) catalyzes the conversion of pyruvate to lactate, with concomitant
oxidation of reduced nicotinamide adenine dinucleotide as the final step in the glycolytic …