Background— Acute kidney injury (AKI) after cardiac surgery is a major health issue.
Lacking effective therapies, risk factor modification may offer a means of preventing this …

Background Antithrombotic therapy in valvular disease is important to mitigate thromboembolism,
but the hemorrhagic risk imposed must be considered. Methods The methods of this …

Concern about risks of allogeneic transfusion has led to an interest in methods for decreasing
perioperative transfusion. To determine whether cell salvage reduces patient exposure to …

We sought to establish the efficacy and safety of prophylactic steroids in adult patients
undergoing cardiopulmonary bypass (CPB). We performed a meta-analysis of randomized trials …

Objectives: Reoperation is a relatively common event in patients with prosthetic heart valves,
but its actual occurrence can vary widely from one patient to another. With a focus on …

Background— Several centers favor replacing a diseased native heart valve with a tissue
rather than a mechanical prosthesis, even in younger adult patients. However, long-term data …

BACKGROUND: We examined factors associated with persistent or recurrent congestive
heart failure after aortic valve replacement. METHODS: Patients who underwent aortic valve …

Background— Observational studies suggest that skeletonization of the internal thoracic
artery (ITA) can improve conduit flow and length and reduce deep sternal infections and …

Objective: The current trend towards decreasing the age for selection of a tissue over a
mechanical prosthesis has led to a dilemma for patients aged 50–65 years. This cohort study …

Objectives: To examine the multiple impacts of valve replacement on the lives of young
adults. Methods: Patients(N=500) between age 18 and 50 who had aortic valve replacement (…