User profiles for Fiona Costello

Fiona Costello

Professor, University of Calgary
Verified email at albertahealthservices.ca
Cited by 7425

Quantifying axonal loss after optic neuritis with optical coherence tomography

F Costello, S Coupland, W Hodge… - Annals of Neurology …, 2006 - Wiley Online Library
Objective To determine to what degree changes in retinal nerve fiber layer (RNFL) thickness
after optic neuritis (ON) correlate with either visual recovery or impairment. Methods ON can …

[HTML][HTML] The OSCAR-IB consensus criteria for retinal OCT quality assessment

P Tewarie, L Balk, F Costello, A Green, R Martin… - PloS one, 2012 - journals.plos.org
Background Retinal optical coherence tomography (OCT) is an imaging biomarker for
neurodegeneration in multiple sclerosis (MS). In order to become validated as an outcome …

Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis

A Petzold, LJ Balcer, PA Calabresi, F Costello… - The Lancet …, 2017 - thelancet.com
Background Structural retinal imaging biomarkers are important for early recognition and
monitoring of inflammation and neurodegeneration in multiple sclerosis. With the introduction …

Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study

…, A Petzold, S Schippling, F Costello… - The Lancet …, 2016 - thelancet.com
Background Most patients with multiple sclerosis without previous optic neuritis have thinner
retinal layers than healthy controls. We assessed the role of peripapillary retinal nerve fibre …

Retinal imaging with optical coherence tomography: a biomarker in multiple sclerosis?

F Costello, JM Burton - Eye and brain, 2018 - Taylor & Francis
Multiple sclerosis (MS) is a progressive neurological disorder characterized by both inflammatory
and degenerative components that affect genetically susceptible individuals. Currently, …

The investigation of acute optic neuritis: a review and proposed protocol

A Petzold, MP Wattjes, F Costello… - Nature Reviews …, 2014 - nature.com
Optic neuritis is an inflammatory optic neuropathy that affects many patients with multiple
sclerosis (MS) at some point during their disease course. Differentiation of acute episodes of MS…

Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria

S Schippling, LJ Balk, F Costello… - Multiple sclerosis …, 2015 - journals.sagepub.com
Background: Retinal optical coherence tomography (OCT) permits quantification of retinal
layer atrophy relevant to assessment of neurodegeneration in multiple sclerosis (MS). …

The afferent visual pathway: Designing a structural‐functional paradigm of multiple sclerosis

F Costello - International Scholarly Research Notices, 2013 - Wiley Online Library
Multiple sclerosis (MS) is a disease of the central nervous system (CNS) believed to arise
from a dysfunctional immune‐mediated response in a genetically susceptible host. The actual …

Differences in retinal nerve fiber layer atrophy between multiple sclerosis subtypes

F Costello, W Hodge, YI Pan, M Freedman… - Journal of the …, 2009 - Elsevier
OBJECTIVES: To determine whether retinal nerve fiber layer (RNFL) atrophy in the afferent
visual pathway may complement existing tools used to describe and characterize differences …

Optic neuritis and autoimmune optic neuropathies: advances in diagnosis and treatment

JL Bennett, F Costello, JJ Chen, A Petzold… - The Lancet …, 2023 - thelancet.com
Optic neuritis is an inflammatory optic neuropathy that is commonly indicative of autoimmune
neurological disorders including multiple sclerosis, myelin-oligodendrocyte glycoprotein …